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- Questions About Raises, Shuttle Fees Top Administrators Forum
A UAMS Update article about Meet Your Administrator”
- Gruenwald Is New U.S. Citizen
Michael Gruenwald becomes U.S. citizen
- Gruenwald Is New U.S. Citizen
Michael Gruenwald becomes U.S. citizen
- Doughnut Sale to Help UAMS Psychiatry Youth Program
A UAMS Update article about a bake sale
- Call-in Announcements, Forums Will Give Employees More Information
A UAMS Update article about plans to improve communication between administration and employees of UAMS Medical Center
- IT Help Desk 400,000th Call Sweepstakes
IT Help Desk 400,000th Call Sweepstates
- The UAMS Help Desk Today - Ten Years Later
The UAMS Help Desk Today - Ten Years Later
- Free Tickets for UAMS Nights at Ray Winder Field
A UAMS Update article about UAMS Night with the Travelers
- ARIA Training Sessions May 19 - June 27 at UAMS
A UAMS Update article about May 19 - June 27 training sessions
- Human Research Forum Is May 21
A UAMS Update article about human research Q & A
- Accolades, May 2003
Accolades to UAMS faculty and staff
- GCRC Deadline Changed to July 1 for Grant Proposals
A UAMS Update article about GCRC pilot grants
- History of the Help Desk
- Watch, Look & Listen: Preview of New UAMS Public Service Campaign
- Forum to Discuss Impact of HIPAA on Research
Update article about HIPAA and research at UAMS
- Human Research Q and A Forum June 27
A UAMS Update article about the human research forum
- Emailed Version of UAMS Notice of Privacy Practices
UAMS Notice of Privacy Practices
- Free UAF Symposium Aug. 14-15 on Evolution of Human Diet
A UAMS Update article about a diet symposium at UAF
- Tom Butler is Arkansas Administrator of the Year
Tom Butler of UAMS Is Arkansas Administrator of the Year
- Join the Prostate Cancer Race Walk. Click Here for Registration Form.*
Join the Prostate Cancer Race Walk. Click Here for Registration Form.
- Join the Prostate Cancer Race Walk. Click Here for Registration Form.*
Join the Prostate Cancer Race Walk. Click Here for Registration Form.
- Defense Department Funds Possible Therapeutic Vaccine for Ovarian Cancer at UAMS
Defense Department Funds Possible Therapeutic Vaccine for Ovarian Cancer at UAMS
- Defense Department Funds Possible Therapeutic Vaccine for Ovarian Cancer at UAMS
Defense Department Funds Possible Therapeutic Vaccine for Ovarian Cancer at UAMS
- Join UAMS/ACRC Team in Race for the Cure®!
Join UAMS/ACRC Team in Race for the Cure!
- Join UAMS/ACRC Team in Race for the Cure®!
Join UAMS/ACRC Team in Race for the Cure!
- UAMS Scientist Receives $272,000 Grant for Tailoring Cancer Treatments with Laser Test
UAMS Scientist Receives $272,000 Grant for Tailoring Cancer Treatments with Laser Test
- UAMS Scientist Receives $272,000 Grant for Tailoring Cancer Treatments with Laser Test
UAMS Scientist Receives $272,000 Grant for Tailoring Cancer Treatments with Laser Test
- Photo Album: Stephens Institute Was a Highlight of Medicine Alumni Reunion
Photo Album: Stephens Institute Was a Highlight of Medicine Alumni Reunion
- Kids First in Fort Smith Celebrated Fourth in Style
Kids First in Fort Smith Celebrated Fourth in Style
- Class of 1948 Dedicates Endowment to Excellence in Education
Class of 1948 Dedicates Endowment to Excellence in Education
- Pharmacy Professor Elected to American College of Clinical Pharmacy
Pharmacy Professor Elected to American College of Clinical Pharmacy
- Pharmaceutical Scientists, Graduate Students Meet at UAMS
Pharmaceutical Scientists, Graduate Students Meet at UAMS
- Stephanie Gardner, Pharm.D., Ed.D., Is Interim Dean of College of Pharmacy
Stephanie Gardner, Pharm.D., Ed.D., Is Interim Dean of College of Pharmacy
- New COPH Survey Research Expert Eager to Develop New Ways of Measuring Public Health
New COPH Survey Research Expert Eager to Develop New Ways of Measuring Public Health
- Ready, Set, Go! UAMS, KATV Launch Get Healthy Arkansas™
UAMS, KATV Launch Get Healthy Arkansas™
- Men to Get off the Sidelines and into the Race in 5K to Raise Money to Fight Prostate Cancer
Men to Get off the Sidelines and into the Race in 5K to Raise Money to Fight Prostate Cancer
- Men to Get off the Sidelines and into the Race in 5K to Raise Money to Fight Prostate Cancer
Men to Get off the Sidelines and into the Race in 5K to Raise Money to Fight Prostate Cancer
- Men to Get off the Sidelines and into the Race in 5K to Raise Money to Fight Prostate Cancer
Men to Get off the Sidelines and into the Race in 5K to Raise Money to Fight Prostate Cancer
- Men to Get off the Sidelines and into the Race in 5K to Raise Money to Fight Prostate Cancer
Men to Get off the Sidelines and into the Race in 5K to Raise Money to Fight Prostate Cancer
- Men to Get off the Sidelines and into the Race in 5K to Raise Money to Fight Prostate Cancer
Men to Get off the Sidelines and into the Race in 5K to Raise Money to Fight Prostate Cancer
- Men to Get off the Sidelines and into the Race in 5K to Raise Money to Fight Prostate Cancer
Men to Get off the Sidelines and into the Race in 5K to Raise Money to Fight Prostate Cancer
- Students Spend Summer as Partners in Research at UAMS
Students Spend Summer as Partners in Research at UAMS
- Students Spend Summer as Partners in Research at UAMS
Students Spend Summer as Partners in Research at UAMS
- Students Spend Summer as Partners in Research at UAMS
Students Spend Summer as Partners in Research at UAMS
- Students Spend Summer as Partners in Research at UAMS
Students Spend Summer as Partners in Research at UAMS
- UAMS Advocates Join BMW Ultimate Drive™ to Support Komen Foundation
: A UAMS Today article about participation in the BMW Ultimate Drive™, a promotion for the Susan G. Komen Breast Cancer Foundation
- UAMS Advocates Join BMW Ultimate Drive™ to Support Komen Foundation
: A UAMS Today article about participation in the BMW Ultimate Drive™, a promotion for the Susan G. Komen Breast Cancer Foundation
- UAMS Advocates Join BMW Ultimate Drive™ to Support Komen Foundation
: A UAMS Today article about participation in the BMW Ultimate Drive™, a promotion for the Susan G. Komen Breast Cancer Foundation
- UAMS Advocates Join BMW Ultimate Drive™ to Support Komen Foundation
: A UAMS Today article about participation in the BMW Ultimate Drive™, a promotion for the Susan G. Komen Breast Cancer Foundation
- Photo Album: Thomas Kieber-Emmons, Ph.D., Is First Josetta Edwards Wilkins, Ed.D., Chair in Breast Cancer Research
Photo Album: Thomas Kieber-Emmons, Ph.D., Is First Josetta Edwards Wilkins, Ed.D., Chair in Breast Cancer Research
- Photo Album: Thomas Kieber-Emmons, Ph.D., Is First Josetta Edwards Wilkins, Ed.D., Chair in Breast Cancer Research
Photo Album: Thomas Kieber-Emmons, Ph.D., Is First Josetta Edwards Wilkins, Ed.D., Chair in Breast Cancer Research
- Photo Album: Thomas Kieber-Emmons, Ph.D., Is First Josetta Edwards Wilkins, Ed.D., Chair in Breast Cancer Research
Photo Album: Thomas Kieber-Emmons, Ph.D., Is First Josetta Edwards Wilkins, Ed.D., Chair in Breast Cancer Research
- Research by Thomas Kieber-Emmons Could Lead to Cancer Vaccines
Research by Thomas Kieber-Emmons Could Lead to Cancer Vaccines
- Research by Thomas Kieber-Emmons Could Lead to Cancer Vaccines
Research by Thomas Kieber-Emmons Could Lead to Cancer Vaccines
- Research by Thomas Kieber-Emmons Could Lead to Cancer Vaccines
Research by Thomas Kieber-Emmons Could Lead to Cancer Vaccines
- UAMS Cancer Researcher Obtains $1.5 Million for Study of Bone Cancer
SEPT. 5, 2003 | Ralph D. Sanderson, Ph.D., of the Arkansas Cancer Research Center (ACRC), part of the University of Arkansas for Medical Sciences (UAMS), has obtained a $1.5 million grant from the National Cancer Institute for his groundbreaking work on the growth of tumor cells in bone.
- UAMS Cancer Researcher Obtains $1.5 Million for Study of Bone Cancer
SEPT. 5, 2003 | Ralph D. Sanderson, Ph.D., of the Arkansas Cancer Research Center (ACRC), part of the University of Arkansas for Medical Sciences (UAMS), has obtained a $1.5 million grant from the National Cancer Institute for his groundbreaking work on the growth of tumor cells in bone.
- “Cure Breast Cancer” Tag Supports Research at UAMS
SEPT. 5, 2003 | The long-awaited Arkansas “Cure Breast Cancer” car license plates are now available – and proceeds go to cancer research at the University of Arkansas for Medical Sciences (UAMS) and to the Susan G. Komen Breast Cancer Foundation.
- “Cure Breast Cancer” Tag Supports Research at UAMS
SEPT. 5, 2003 | The long-awaited Arkansas “Cure Breast Cancer” car license plates are now available – and proceeds go to cancer research at the University of Arkansas for Medical Sciences (UAMS) and to the Susan G. Komen Breast Cancer Foundation.
- “Cure Breast Cancer” Tag Supports Research at UAMS
SEPT. 5, 2003 | The long-awaited Arkansas “Cure Breast Cancer” car license plates are now available – and proceeds go to cancer research at the University of Arkansas for Medical Sciences (UAMS) and to the Susan G. Komen Breast Cancer Foundation.
- UAMS Laser Scientist “Tags” Gold Particle Targets to Kill Breast Cancer Cells
SEPT. 10, 2003 | Vladimir P. Zharov, Ph.D., a biomedical laser research pioneer at the University of Arkansas for Medical Sciences (UAMS), has won a prestigious grant from the U.S. Department of Defense to investigate a new way to kill breast cancer cells using laser radiation and gold nanoparticles.
- UAMS Laser Scientist “Tags” Gold Particle Targets to Kill Breast Cancer Cells
SEPT. 10, 2003 | Vladimir P. Zharov, Ph.D., a biomedical laser research pioneer at the University of Arkansas for Medical Sciences (UAMS), has won a prestigious grant from the U.S. Department of Defense to investigate a new way to kill breast cancer cells using laser radiation and gold nanoparticles.
- UAMS Laser Scientist “Tags” Gold Particle Targets to Kill Breast Cancer Cells
SEPT. 10, 2003 | Vladimir P. Zharov, Ph.D., a biomedical laser research pioneer at the University of Arkansas for Medical Sciences (UAMS), has won a prestigious grant from the U.S. Department of Defense to investigate a new way to kill breast cancer cells using laser radiation and gold nanoparticles.
- UAMS Surgeon to Give Breast Cancer Update March 8 at Air Force Base
- UAMS Surgeon to Give Breast Cancer Update March 8 at Air Force Base
- "Imus in the Morning" Praises Two UAMS Doctors
UAMS doctors James Suen and Gazi Yasargil cited by Don Imus on national radio program
- "Imus in the Morning" Praises Two UAMS Doctors
UAMS doctors James Suen and Gazi Yasargil cited by Don Imus on national radio program
- "Imus in the Morning" Praises Two UAMS Doctors
UAMS doctors James Suen and Gazi Yasargil cited by Don Imus on national radio program
- "Imus in the Morning" Praises Two UAMS Doctors
UAMS doctors James Suen and Gazi Yasargil cited by Don Imus on national radio program
- ACRC Auxiliary’s Annual Cooks Tour Raises More than $50,000 for Family Home; Ronda Henry Tillman, M.D., Is Honored with Special Award
MAY 3, 2004 | It was the perfect way to spend a Sunday afternoon – enjoying delicious food prepared by some of Little Rock’s finest chefs and touring four beautiful homes in the Sologne area of Chenal Valley as the Arkansas Cancer Research Center (ACRC) Auxiliary held its annual Cooks Tour fund-raiser, April 25.
- ACRC Auxiliary’s Annual Cooks Tour Raises More than $50,000 for Family Home; Ronda Henry Tillman, M.D., Is Honored with Special Award
MAY 3, 2004 | It was the perfect way to spend a Sunday afternoon – enjoying delicious food prepared by some of Little Rock’s finest chefs and touring four beautiful homes in the Sologne area of Chenal Valley as the Arkansas Cancer Research Center (ACRC) Auxiliary held its annual Cooks Tour fund-raiser, April 25.
- ACRC Auxiliary’s Annual Cooks Tour Raises More than $50,000 for Family Home; Ronda Henry Tillman, M.D., Is Honored with Special Award
MAY 3, 2004 | It was the perfect way to spend a Sunday afternoon – enjoying delicious food prepared by some of Little Rock’s finest chefs and touring four beautiful homes in the Sologne area of Chenal Valley as the Arkansas Cancer Research Center (ACRC) Auxiliary held its annual Cooks Tour fund-raiser, April 25.
- ACRC Auxiliary’s Annual Cooks Tour Raises More than $50,000 for Family Home; Ronda Henry Tillman, M.D., Is Honored with Special Award
MAY 3, 2004 | It was the perfect way to spend a Sunday afternoon – enjoying delicious food prepared by some of Little Rock’s finest chefs and touring four beautiful homes in the Sologne area of Chenal Valley as the Arkansas Cancer Research Center (ACRC) Auxiliary held its annual Cooks Tour fund-raiser, April 25.
- Barlogie Receives Distinction for Career of Fighting Myeloma
May 18, 2004 | Dr. Bart Barlogie’s career has taken him to many far-flung locations but always in the same direction. Finding a cure for multiple myeloma has been Barlogie’s prime motivation for almost 30 years, and it was with that goal in mind that the International Myeloma Foundation honored him with the Robert A. Kyle Lifetime Achievement Award May 8 at a special event held at the Peabody Little Rock.
- Barlogie Receives Distinction for Career of Fighting Myeloma
May 18, 2004 | Dr. Bart Barlogie’s career has taken him to many far-flung locations but always in the same direction. Finding a cure for multiple myeloma has been Barlogie’s prime motivation for almost 30 years, and it was with that goal in mind that the International Myeloma Foundation honored him with the Robert A. Kyle Lifetime Achievement Award May 8 at a special event held at the Peabody Little Rock.
- Barlogie Receives Distinction for Career of Fighting Myeloma
May 18, 2004 | Dr. Bart Barlogie’s career has taken him to many far-flung locations but always in the same direction. Finding a cure for multiple myeloma has been Barlogie’s prime motivation for almost 30 years, and it was with that goal in mind that the International Myeloma Foundation honored him with the Robert A. Kyle Lifetime Achievement Award May 8 at a special event held at the Peabody Little Rock.
- Barlogie Receives Distinction for Career of Fighting Myeloma
May 18, 2004 | Dr. Bart Barlogie’s career has taken him to many far-flung locations but always in the same direction. Finding a cure for multiple myeloma has been Barlogie’s prime motivation for almost 30 years, and it was with that goal in mind that the International Myeloma Foundation honored him with the Robert A. Kyle Lifetime Achievement Award May 8 at a special event held at the Peabody Little Rock.
- UAMS Receives $541,495 in National Settlement Over Taxol Cost
JUNE 14, 2004 | Cancer programs at the University of Arkansas for Medical Sciences will receive $541,495 as part of a national settlement with Bristol-Myers Squibb, which manufacturers the cancer-fighting drug Taxol.
- UAMS Receives $541,495 in National Settlement Over Taxol Cost
JUNE 14, 2004 | Cancer programs at the University of Arkansas for Medical Sciences will receive $541,495 as part of a national settlement with Bristol-Myers Squibb, which manufacturers the cancer-fighting drug Taxol.
- UAMS Receives $541,495 in National Settlement Over Taxol Cost
JUNE 14, 2004 | Cancer programs at the University of Arkansas for Medical Sciences will receive $541,495 as part of a national settlement with Bristol-Myers Squibb, which manufacturers the cancer-fighting drug Taxol.
- UAMS Receives $541,495 in National Settlement Over Taxol Cost
JUNE 14, 2004 | Cancer programs at the University of Arkansas for Medical Sciences will receive $541,495 as part of a national settlement with Bristol-Myers Squibb, which manufacturers the cancer-fighting drug Taxol.
- Sturgis Trust Gives $500,000 for Rural Cancer Screenings
Sturgis Trust offers $500,000 grant for cancer screenings in rural Arkansas
- Sturgis Trust Gives $500,000 for Rural Cancer Screenings
Sturgis Trust offers $500,000 grant for cancer screenings in rural Arkansas
- "Annals of Surgery" Reports UAMS Breast Biopsy Technique
ANNALS OF SURGERY reports new technique developed at UAMS Medical Center for breast cancer biopsy
- "Annals of Surgery" Reports UAMS Breast Biopsy Technique
ANNALS OF SURGERY reports new technique developed at UAMS Medical Center for breast cancer biopsy
- "Annals of Surgery" Reports UAMS Breast Biopsy Technique
ANNALS OF SURGERY reports new technique developed at UAMS Medical Center for breast cancer biopsy
- UAMS Researcher Wins International Award for Ovarian Cancer Research
JULY 9, 2004 | O’Brien, Ph.D., professor in the Department of Obstetrics and Gynecology in the University of Arkansas for Medical Sciences (UAMS) College of Medicine and director of UAMS Arkansas BioVentures, recently won the coveted Abbott Award in recognition of a lifetime of work in the area of ovarian cancer research.
- UAMS Researcher Wins International Award for Ovarian Cancer Research
JULY 9, 2004 | O’Brien, Ph.D., professor in the Department of Obstetrics and Gynecology in the University of Arkansas for Medical Sciences (UAMS) College of Medicine and director of UAMS Arkansas BioVentures, recently won the coveted Abbott Award in recognition of a lifetime of work in the area of ovarian cancer research.
- UAMS Researcher Wins International Award for Ovarian Cancer Research
JULY 9, 2004 | O’Brien, Ph.D., professor in the Department of Obstetrics and Gynecology in the University of Arkansas for Medical Sciences (UAMS) College of Medicine and director of UAMS Arkansas BioVentures, recently won the coveted Abbott Award in recognition of a lifetime of work in the area of ovarian cancer research.
- UAMS Researcher Wins International Award for Ovarian Cancer Research
JULY 9, 2004 | O’Brien, Ph.D., professor in the Department of Obstetrics and Gynecology in the University of Arkansas for Medical Sciences (UAMS) College of Medicine and director of UAMS Arkansas BioVentures, recently won the coveted Abbott Award in recognition of a lifetime of work in the area of ovarian cancer research.
- Cancer Care at ACRC of UAMS Ranked High by U.S. News & World Report
Cancer Care at UAMS ranked high with USN&WR
- Cancer Care at ACRC of UAMS Ranked High by U.S. News & World Report
Cancer Care at UAMS ranked high with USN&WR
- Cancer Care at ACRC of UAMS Ranked High by U.S. News & World Report
Cancer Care at UAMS ranked high with USN&WR
- UAMS Promises Cancer Treatment with Loving Care, Devotion
UAMS physicians and leaders stress patient care with caring and compassion
- UAMS Promises Cancer Treatment with Loving Care, Devotion
UAMS physicians and leaders stress patient care with caring and compassion
- UAMS Promises Cancer Treatment with Loving Care, Devotion
UAMS physicians and leaders stress patient care with caring and compassion
- UAMS to Create Myeloma Institute
UAMS announces Myeloma Institute for Research and Therapy
- UAMS to Create Myeloma Institute
UAMS announces Myeloma Institute for Research and Therapy
- Center for Rural Health Presents CME/CE Lecture: "Major Depressive Disorder-Diagnosis and Treatment"
Center for Rural Health Presents CME/CE Lecture: "Major Depressive Disorder-Diagnosis and Treatment"
- Center for Rural Health Presents CME/CE Lecture: "Major Depressive Disorder-Diagnosis and Treatment"
Center for Rural Health Presents CME/CE Lecture: "Major Depressive Disorder-Diagnosis and Treatment"
- UAMS Hosts Monthly Nutrition Seminar Feb. 9
UAMS Hosts Monthly Nutrition Seminar Feb. 9
- UAMS Hosts Monthly Nutrition Seminar Feb. 9
UAMS Hosts Monthly Nutrition Seminar Feb. 9
- Enterprise Server Replacement
Enterprise Server Replacement
- Occupational Health & Safety Survey
Occupational Health & Safety Survey
- Occupational Health & Safety Survey
Occupational Health & Safety Survey
- Bookstore Offers 40 Percent Discount on Russell Jerzee Apparel
Bookstore Offers 40 Percent Discount on Russell Jerzee Apparel
- Bookstore Offers 40 Percent Discount on Russell Jerzee Apparel
Bookstore Offers 40 Percent Discount on Russell Jerzee Apparel
- UAMS Opens Code Moo Frozen Yogurt Shop
UAMS Opens Code Moo Frozen Yogurt Shop
- UAMS Opens Code Moo Frozen Yogurt Shop
UAMS Opens Code Moo Frozen Yogurt Shop
- UAMS Hosts Blood Drives in COPH, Freeway Medical
UAMS Hosts Blood Drives in COPH, Freeway Medical
- UAMS Hosts Blood Drives in COPH, Freeway Medical
UAMS Hosts Blood Drives in COPH, Freeway Medical
- TIAA-CREF on Campus in February and March
TIAA-CREF on Campus in February and March
- TIAA-CREF on Campus in February and March
TIAA-CREF on Campus in February and March
- Human Resources Hosts 'HR Connects!' Feb. 16
Human Resources Hosts 'HR Connects!' Feb. 16
- Human Resources Hosts 'HR Connects!' Feb. 16
Human Resources Hosts 'HR Connects!' Feb. 16
- Arm protection System (APS) for robotic surgery: A surgical device to position the arms of surgical patients during prolonged robotic surgical procedures. (11-04)
A device to secure and position the arms of patients during prolonged surgical procedures to protect against nerve damage and assist the anesthesiologist access to IV sites.
- Arm protection System (APS) for robotic surgery: A surgical device to position the arms of surgical patients during prolonged robotic surgical procedures. (11-04)
A device to secure and position the arms of patients during prolonged surgical procedures to protect against nerve damage and assist the anesthesiologist access to IV sites.
- Novel plasma biomarker and marker profiles for analysis of metastatic disease: A unique fragment of parathyroid hormone related protein predicts breast metastasis to bone (11-09)
Novel biomarker profile for the management of metastisis to bone of patients with breast cancer.
- Novel plasma biomarker and marker profiles for analysis of metastatic disease: A unique fragment of parathyroid hormone related protein predicts breast metastasis to bone (11-09)
Novel biomarker profile for the management of metastisis to bone of patients with breast cancer.
- Novel plasma biomarker and marker profiles for analysis of metastatic disease: A unique fragment of parathyroid hormone related protein predicts breast metastasis to bone (11-09)
Novel biomarker profile for the management of metastisis to bone of patients with breast cancer.
- Gray’s Anomaly: A Source of Empowerment
Feb. 8, 2012 | “I’ll trim it so it’s not so bulky,” James Y. Suen, M.D., said as he folded, then snipped a tiny edge of gauze off before he placed it on his patient’s right jaw. He has cared for 23-year-old Jasmine Gray ever since she was 11 when she traveled from Memphis, Tenn. to see him after first being misdiagnosed.
- Need Something Sweet for Your Valentine?
Need Something Sweet for Your Valentine?
- Need Something Sweet for Your Valentine?
Need Something Sweet for Your Valentine?
- Code Moo Now Open
Code Moo Now Open
- Code Moo Now Open
Code Moo Now Open
- Sign Up for the UAMS House of Delegates Relay for Life Team
UAMS House of Delegates Relay for Life Team
- Sign Up for the UAMS House of Delegates Relay for Life Team
UAMS House of Delegates Relay for Life Team
- Overwhelming Response to SmartCare
Overwhelming Response to SmartCare
- Overwhelming Response to SmartCare
Overwhelming Response to SmartCare
- Celebrating African American Women Firsts
Celebrating African American Women Firsts
- Celebrating African American Women Firsts
Celebrating African American Women Firsts
- Nutrition Department Hosts Food Drive
Nutrition Department Hosts Food Drive
- Nutrition Department Hosts Food Drive
Nutrition Department Hosts Food Drive
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A researcher at the University of Arkansas for Medical Sciences (UAMS) has won a National Institutes of Health (NIH) grant for experiments that could lead to new therapies for controlling the spread of disease agents, including metastacizing cancer cells.
The UAMS study seeks to understand the fundamentals of lymphatic function. A new way to clearly see the flow of lymphatic fluid at the cellular level could unlock the mystery of how metastatic cancer cells migrate through the body.
Vladimir P. Zharov, Ph.D., is developing a high-resolution, high-contrast laser imaging system to observe cells as they move through the lymph system inside a living organism, something that so far has not been viewed. The study will focus the diagnostic laser equipment on the mesentery, the ultra-thin lining attached to the abdominal wall containing a single layer of blood and lymph microvessels.
“It is surprising that so little is known of microlymphatic fundamentals, including mechanism of propulsion, valve function, and other things,” Zharov, director of the Phillips Classic Laser Laboratory in the Arkansas Cancer Research Center at UAMS, said. “To date, blood microcirculation has been studied in detail, while the lymphatic system has been paid much less attention.”
The laser technique will allow visualization of even single cells in blood and lymphatic microvessels, including red blood cells, leukocytes, and platelets. It will also allow scientists to measure lymphatic flow, creating what is called the “velocity profile.” Zharov even hopes to be able to estimate the viscosity of the lymph fluid.
Because several diseases, including lymphedema, lymphatic malformations, port-wine stains, and cancer, disrupt lymphatic function, Zharov’s optical laser system has a broad spectrum of possible biomedical applications.
The grant of $417,277 for two years is from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) at NIH. One of the long-term goals of the study is to test the laser system’s capability for studying how the microvascular system reacts to various therapies, such as drugs or laser treatment, including a study of micro injury to the vessels’ walls.
Zharov, who came to UAMS from his native Moscow in 2000, also is investigating a laser-based treatment of lymphedema (limb swelling) after breast cancer surgery, a way to customize chemotherapy using laser technology, and a way to bind breast cancer cells with tiny gold particles in order to kill the cells with a laser pulse.
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