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News from the University of Arkansas for Medical Sciences 

UAMS Myeloma Researcher Wins $100,000 Grant

JAN. 24, 2003 | A researcher in the Myeloma Institute for Research and Therapy at the University of Arkansas for Medical Sciences (UAMS) has received a one-year, $100,000 research grant.

Frits van Rhee, M.D., Ph.D., director of Imunotherapy at the institute and associate professor in the College of Medicine was one of six researchers from around the country selected to receive a Senior Research Award from the Multiple Myeloma Research Foundation (MMRF).

The grant will help fund Dr. van Rhee’s work with myeloma-specific cytotoxic cells. “What we’re trying to do is make white blood cells which are going to specifically kill myeloma cells,” he said. “We’ve identified two proteins which are unique to myeloma and other cancers. We make these proteins in the laboratory, then give these proteins to specialized immune cells. These immune cells can stimulate other white blood cells to grow out and become specific for this protein.” Dr. van Rhee said his project is experimenting both with expressing the whole protein and with transferring them to genes for a form of gene therapy against myeloma cells.

After serving a fellowship at Oxford, Dr. van Rhee earned a Ph.D. in immunology at the Royal Post Graduate Medical School in London . He moved to the United States, where he was first a visiting associate professor at the National Institutes of Health, and then associate professor of Medicine at the University of South Carolina before moving to UAMS in 2001.

MMRF was founded in 1998 by twin sisters Karen Andrews and Kathy Gusti after Kathy was diagnosed with multiple myeloma. The Senior Research Awards were presented Jan. 6. An associate of Dr. van Rhee on the project at UAMS, Ramesh Batchu, Ph.D., won a Junior Research Award from MMRF in November.

“It allows us to continue the work that we are currently doing,” Dr. van Rhee said. “It will be very important for us to be able to meet salary obligations and obtain necessary equipment. So I think it’s very important.”


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Links on This Page

Myeloma Institute for Research and Therapy: http://myeloma.uams.edu/

Frits van Rhee, M.D., Ph.D.:  http://myeloma.uams.edu/vanrhee.asp

Multiple Myeloma Research Foundation:  www.multiplemyeloma.org

Ramesh Babu Batchu, Ph.D.:  http://myeloma.uams.edu/Batchu.asp

New Gift Will Help UAMS Shine "Floodlight" on Genetics of Multiple Myeloma http://www.uams.edu/today/2002/121802/newgift.htm

Japanese TV Crew Interviews UAMS’s Bart Barlogie, M.D., Ph.D.:  http://www.uams.edu/today/2002/120602/barlogiejapan.htm

Audio – Barlogie, Japanese TV Interview:  http://www.uams.edu/htyh/12-02/barlogie.htm


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03/29/05