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News from the University of Arkansas for Medical Sciences
Research
at UAMS Today: A Better Cure for the Common Wart
MAY 6, 2002 |
Dermatologists at the University of Arkansas for Medical
Sciences (UAMS) have developed a new treatment for
common warts that appears to be more successful than any
standard method. (See video.)
Thomas Horn, M.D., chair of the Dermatology
Department in the UAMS College of Medicine, and
Sandra Marchese Johnson, M.D., an assistant professor in
the department, have found they can stimulate the body
to fight and destroy all warts by injecting a single
wart with approved skin test antigens.
The treatment was successful in 74 percent of patients
in a pilot study. Drs. Horn and Johnson reported the
success of their pilot study in the journal Archives
of Dermatology in April 2001, collaborating with
UAMS biostatistician Paul K. Roberson, Ph.D. They now
are recruiting volunteers with warts for more clinical
trials of this treatment.
The researchers have obtained a patent for the novel
treatment and plan to manufacture their new medicine for
warts.
Arkansas
BioVentures, a UAMS program that provides
technical support for new companies manufacturing
innovative drugs or other biotechnology products, will
assist in development of the company.
Drs. Horn and Johnson began experimenting with
immunotherapy for common warts in 1999, thanks to
research grants from the Biomedical Research Foundation,
the Dermatology Foundation, UAMS pilot study grants,
National Institutes of Health funding from the UAMS
General Clinical Research Center, and the Arkansas
Science and Technology Authority.
Dr. Horn is a graduate of the University of Virginia
School of Medicine, was a resident in dermatology at the
University of Maryland, and completed a fellowship in
dermatopathology at Johns Hopkins University School of
Medicine.
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Sandra
Marchese Johnson, M.D., and Thomas Horn, M.D., examine a
patient during shooting of the video “A Better Cure for
the Common Wart.” (Keith Freeman)
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Dr.
Johnson attended Northeastern Ohio Universities College of
Medicine and completed a residency in dermatology in the UAMS
College of Medicine. She is director of the Dermatology Clinical
Trials Unit at UAMS and treats adult and pediatric patients in
the UAMS Dermatology Clinic, UAMS Laser and Cosmetic Surgery
Center, and at Central Arkansas Veterans Healthcare System.
Wesley Burks, M.D., an immunologist in the College of Medicine
and director of the Arkansas
Children’s Hospital Research Institute, and Ricki Helm,
Ph.D., of Arkansas Children’s Hospital, are collaborating with
Drs. Horn and Johnson in the trial of mumps-candida-trichophyton
immunotherapy for warts.
”We hope to unlock the secrets of why some people get warts as
well as why some people have difficulty ridding themselves of
warts,” Dr. Johnson said.
Links
on This Page
Video: http://www.uams.edu/today/2002/042502/video.htm
Bioventures Board: http://www.uams.edu/today/2002/041102/bioventures.htm
Safe Foods: http://www.uams.edu/today/2002/040402/safe.htm
Fifty for the Future: http://www.uams.edu/today/2002/031402/bioventures.htm
Dermatologist, Banker: http://www.uams.edu/today/051701/forum.htm
E-mail: http://www.uams.edu/today/051001/parade.htm
Newsletter: InstitutionalAdvancement@uams.edu
Dermatology Department: http://www.uams.edu/dermatology/default.htm
Arkansas BioVentures: http://www.arkansas-bioventures.uams.edu/
Arkansas Children’s Hospital Research Institute: http://achri.ach.uams.edu/
© 2002 University of Arkansas for
Medical Sciences (UAMS). A single copy of these materials may be
reprinted for noncommercial personal use only. “UAMS,”
“UAMS Medical Center,” “UAMS Online,” “UAMS Today,”
“uams.edu,” and “Here’s to Your Health” are marks of
UAMS.
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08/15/03 |
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