Preliminary Results
Our preliminary results support the notion that phospholipid and fatty acid abnormalities occur in the brain in schizophrenia.  The full study, which is funded by the National Institute of Mental Health, is currently in progress, and results are not yet available.  The results of this study will provide significant information concerning the role of brain phospholipids and fatty acids in schizophrenia.

References

1. Pearce JM, Komoroski RA. Analysis of phospholipid molecular species in brain by 31P NMR spectroscopy. Magn Reson Med 2000;44:215-223.
2. Komoroski RA, Pearce JM, Griffin STW, Mrak RE, Omori M, Karson CN. Phospholipid abnormalities in postmortem schizophrenic brains detected by 31P nuclear magnetic resonance spectroscopy: a preliminary study. Psychiatry Res: Neuroimaging 2001;106:171-180.

Richard A. Komoroski, Ph.D.
Dr. Komoroski is the principal investigator on this project, as well as the MRS of PTSD study.  The UAMS Radiology faculty information page contains further information on Dr. Komoroski.

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