Access to the fetal brain is limited primarily by the position of the fetal
head and technical factors such as maternal body habitus. The diagnosis of
brain anomalies in the fetus therefore has to depend upon constant landmarks
that could be documented in normal fetuses. The cerebellum, cisterna magna,
cavum septum pellucidum, and ventricular atria are such constant landmarks.
When these normal structures are documented, the vast majority of congenital
brain anomalies can be reliably excluded. If an abnormality is documented at
any of these levels, neonatal correlation of the abnormality becomes possible
because these same landmarks can be reliably reproduced in the neonate, using
the transfontanel/mastoid approach. It is therefore possible to navigate the
fetal and neonatal brain once the examiner becomes familiar with these
structures and has learned the skill to consistently demonstrate them in both
the normal and abnormal setting.
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