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Chairman’s Welcome

Welcome to the Department of Physiology and Biophysics at the University of Arkansas for Medical Sciences.  The Department of Physiology and Biophysics is one of five basic science departments in the College of Medicine.  There are currently 19 primary faculty in the department.  An additional 24 faculty from eight other departments in the College of Medicine have secondary appointments in the Department of Physiology and Biophysics.   

Education:  Our educational mission is to teach medical students (in Medical Physiology, Medical Cell Biology, summer research projects, and senior electives) and graduate students in the departmental Master of Science and Doctor of Philosophy programs as well as in the newly established interdisciplinary (IBS) Ph.D. Program.  Within the Physiology and Biophysics Ph.D. Program, doctoral students may choose to enter specialized tracks in Pathophysiology or Neuroscience.  Currently, the departmental graduate program includes 23 students pursuing the Ph.D. and 5 students pursuing the M.S. degree.

Research:  The research mission of the department is to carry out high quality, extramurally funded research that has lasting impact on basic knowledge and human health.  A central theme in the department is the regulation of life processes, studied mainly at the level of the cell.  Departmental research programs focus on many aspects of physiological regulation, including gene transcription, protein targeting, post-translational protein modification, subcellular signaling, cell-cell communication, and  control of growth and differentiation.  Another major theme in the department is membrane biology, e.g., membrane receptors, ion  channels, transporters, and subcellular membrane trafficking.  The experimental systems of interest to faculty in the department include musculoskeletal, vascular, respiratory, gastrointestinal, renal, central nervous system, as well as model cells and organisms (see individual faculty pages). 

Research funding in the department has increased dramatically over the past several years.  In the most recent national rankings (2005), the department ranked 36th among physiology departments in NIH funding.Faculty research is supported by the National Institutes of Health, National Science Foundation, United States Department of Agriculture, National Aeronautics and Space Administration, American Cancer Society, and the National Multiple Sclerosis Society.  Two major federally funded programs at UAMS are led by departmental faculty: the United States Departmental of Agriculture Arkansas Children’s Nutrition Center, directed by Thomas M. Badger, and the National Institutes of Health IDeA Network of Biomedical Research Excellence (INBRE), directed by Lawrence E. Cornett.

Facilities:  In February, 2004, the department moved into the second floor of the new Biomedical Research Center Building 2, adjacent to existing departmental space in the original Biomedical Research Center.  Within this space, individual laboratories and departmental shared facilities contain a wide array of equipment needed for research in modern cellular and molecular biology.  A new Zeiss confocal microscope purchased from an NIH Shared Instrumentation Grant was installed in the department in the fall of 2005.  A protein crystallography laboratory, equipped with a Rigaku R-axis  X-ray diffractometer, was established in the fall of 2006 by new faculty members K.I. Varughese and R. Celikel. Other shared facilities are available on campus, including DNA microarray protein mass spectrometry and proteomics, skeletal imaging, PET imaging, nuclear magnetic resonance, DNA sequencing, and transgenic mouse preparation.  The   physical facilities and collegial atmosphere make the Department of Physiology and Biophysics an excellent place to pursue career opportunities in biomedical research.

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