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 Michael E. Soulsby
Associate Professor
Ph.D., West Virginia University
Office:
(501) 686-5127
Lab: (501) 686-5127
Email: SoulsbyMichaelE@uams.edu
Our laboratory is interested in the influence of space travel,
with its associated weightlessness, on body function. We have perfected a
land-based, rat, tail-suspension model of exposure to microgravity. Using
this model, we have continuously and telemetrically monitored changes in
heart rate, arterial pressure, body temperature, body activity, and the
electrocardiogram during weeks of suspension. We have followed circadian
rhythm changes in these parameters before, during, and after suspension. We
have monitored bone density loss and muscle atrophy resulting from hind limb
unloading. We have studied brain stress during suspension, by measuring
changes in brain lipid peroxidation. We have followed changes in pancreatic
function during prolonged hind-limb suspension. Currently, we are
investigating changes in vascular and intestinal smooth muscle mechanical
function using this model.
Dr. Soulsby's
Laboratory Homepage
Representative Publications
Soulsby ME,
Phillips B, and P. Chowdhury. (2004) The Effects of Soy-Protein Diet on
Elevated Brain Lipid Peroxide Levels Induced by Simulated Weightlessness.
Annals Clin. And Lab. Science, 34(1): 103-106.
Chowdhury P. and ME Soulsby. (2002) Lipid Peroxidation
in Rat Brain is Increased by Simulated Weightlessness and Decreased by a
Soy Protein Diet. Annals Clin. and Laboratory Science 32(2): 188-192.
Soulsby ME
et al. (2000) Evaluation of the Purilens Contact Lens Care System – An
Automatic Care System Incorporating UV Disinfection and Hydrodynamic Shear
Cleaning. CLAO J. 26(3): 134-140.
Morgan K, Burns ER, Pasley J, Greenwood M, Byars A, Soulsby ME. (2000) The
Effect of Chronobiology on Athletic Performance: The Optimal Use of
Circadian Rhythms to Enhance Athletic Performance. Applied Research in
Coaching and Athletics Annual Volume 15, Pages 101-121.
Chowdhury, P, Soulsby, ME, and JN Pasley. (1999) Distribution
of 3H-nicotine in rat tissues under the influence of simulated
microgravity. Biomed. Environ. Sci. 12:103-109.
Link
to Dr. Soulsby at Pub-Med
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