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REGULATION OF PROKARYOTIC & EUKARYOTIC

Fall 2009 - GENE EXPRESSION (5143)

Rayford Auditorium Room 106-2

Biomedical Research Center II

Tuesdays & Thursdays

9:00 am – 11:00 am 

Course Director: Patricia Wight

 

Class Updates

Date Information

8/18

Welcome to Gene Expression

9/10

Dr. Benes has revised her slides for GGE06 and added optional reading articles

9/11

Dr. Raney has added reading articles for GGE07
9/15 Dr. Raney has revised the slides for GGE08

Lecture Slides and Readings are located on ERES

DATE

LECTURE

INSTRUCTOR

Tue,   08/18/09

GE01 Prokaryotic Genome Organization

Mark Smeltzer

Thur, 08/20/09

GE 02 Operons

Mark Smeltzer

Tue,   08/25/09

GE03 Prokaryotic transcription

Chia Lee

Thur, 08/27/09

GE04 Regulation of prokaryotic transcription

Chia Lee

Tue,   09/01/09

GE05 Prokaryotic replication, repair and recombination

Kevin Raney

Thur, 09/03/09

EXAM 1 (8:30 – 11:30 AM)

Includes lectures from Smeltzer, Lee & Raney

 

Tue,   09/08/09

GE06 Eukaryotic Genome Organization

Helen Benes

Thur, 09/10/09

GE07 Eukaryotic replication and repair

Kevin Raney

Tue,   09/15/09

GE08 Eukaryotic replication and repair

Kevin Raney

Thur, 09/17/09

GE09 Eukaryotic Transcription

Patricia Wight

Tue,   09/22/09

GE10 Eukaryotic Transcription

Patricia Wight

Thur, 09/24/09

GE11 Eukaryotic Transcription

Patricia Wight

Tue,   09/29/09

GE12 Eukaryotic Transcription

Patricia Wight

Thur, 10/01/09

GE13 Eukaryotic Gene Regulation

Helen Benes

Tue,   10/06/09

EXAM 2 (8:30 – 11:30 AM)

Includes lectures from Benes, Raney & Wight

 

Thur, 10/08/09

GE14 Meiosis and Mitosis

Wayne Wahls

Tue,   10/13/09

GE15 Meiosis and Mitosis

Wayne Wahls

Thur, 10/15/09

GE16 Genetic Recombination

Wayne Wahls

Tue,   10/20/09

GE17 Posttranscriptional processing

Xuming Zhang

Thur, 10/22/09

GE18 RNA splicing

Xuming Zhang

Tue,   10/27/09

GE19 RNA splicing

Xuming Zhang

Thur, 10/29/09

GE20 Reverse transcription

Xuming Zhang

Tue,   11/03/09

EXAM 3 (8:30 – 11:30 AM)

Includes lectures from Wahls & Zhang

 

Thur, 11/05/09

GE21 Prokaryotic & Regulation of prokaryotic translation

Angus MacNicol

Tue,   11/10/09

GE22 Eukaryotic translation

Angus MacNicol

Thur, 11/12/09

GE23 Regulation of eukaryotic translation

Angus MacNicol

Tue,   11/17/09

GE24 Eukaryotic Differentiation & Development

Mari Davidson

Thur, 11/19/09

GE25 Eukaryotic Differentiation & Development

Mari Davidson

Tue,   11/24/09

EXAM 4 (8:30 – 11:30 AM)

Includes lectures from MacNicol & Davidson

 

Prerequisites:                It is recommended that the student has had an undergraduate course in biochemistry or molecular biology.

Objectives:                   The goal of this course is for students to acquire a working knowledge of the various methods by which gene expression can be controlled.  A side-by-side comparison of these mechanisms for both prokaryotes and eukaryotes will be explored.  It is anticipated that at the end of this course, students will become proficient at reading the primary literature in gene regulation.

 Course Structure:        The course is 3 credit hours which meets twice a week for 2 hours per session.  The course will be conducted by didactic lectures, as well as, class discussion of current reviews and primary papers.  The students will be assigned a grade solely based on exams.  Grades will be scaled with the class average @ B.

 Reading Material:        Readings will mainly consist of recent reviews and primary articles as assigned by the individual Instructors.  Genes IX, by Benjamin Lewin is recommended as a text for general background.  A copy of the text has been placed on reserve in the library.

 Course Evaluation:      The course will be evaluated by the students as per standard UAMS procedures.  Each Instructor will also be evaluated by the students.
 

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