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CELLULAR ENDOCRINOLOGY (5033)
TUESDAY AND THURSDAY
(1:00 P.M. to 2:30 P.M.)

Course Director: Dana Gaddy, Ph.D.

Class Updates

Date Information

8/19

Welcome to Cellular Endocrinology

8/25

Dr. Soulsby has posted a reading assignment for lecture CE04 on ERES

9/5

Dr. McGehee has no slides for lecture CE07

9/9

Dr. Gaddy has posted a reading assignment for lecture CE08, Read before class

Lecture Slides and Readings are located on ERES

GENERAL COMMENTS: All lectures and examinations and student presentations will be held in the Physiology Conference Room in Biomed 2 (242-2).

1.         Lectures:  Tuesday and Thursday: 1:00 p.m. - 2:30 p.m.

2.         Reading Material:  Reading material and copies of slides will be supplied             by instructors a few days in advance of each lecture.

3.         Examinations:  Three (3) exams with points distributed equally for               each lecture (10 points per lecture) Exam 1 = 110 points; Exam 2 = 90 points;           Exam 3 = 80 points; Student Presentations and Written Report = 30 points

4.        Questions:  Exam questions may be either objective (e.g. multiple choice,             matching or true/false), short answer, essay, or any combination thereof.

5.         Dates and times for Examinations:

            EXAM #1        September 30, 2008     Tuesday          1:00 - 4:00 p.m.

            EXAM #2        November 6, 2008       Thursday         1:00 - 4:00 p.m.

            EXAM #3        December 18, 2008     Thursday          1:00 - 4:00 p.m.  

6.         Grading:

                                                90 - 100%       A

                                                80 -   89%       B

                                                70 -   79%       C

            The above scale of grades is meant to be a general guideline.  Letter grades             may be adjusted to a lower percentage score, but will not be raised to a             higher percentage score.       

7.         Microarray Project:  Students will be provided a data set for analysis.             Specific instructions will be provided at the time of the project start. A brief              4-5 page written report will be due on the day of the student seminar..

8.         Seminars:  Each student will be responsible for giving a 20-minute presentation on their analysis of the microarray data set, the genes they have identified for validation, and the biological rationale for choosing those genes.

Date

Lecture #

Lecture

Instructor

8/19/08

CE01

Receptor serine kinases

Gaddy

8/21/08

CE02

Receptor tyrosine kinases

Kurten

8/26/08

CE03

Ion channels in endocrine signal transduction

Jennings

8/28/08

CE04

Erythropoietin and its role of erythropoiesis

Soulsby

9/02/08

CE05

Prostaglandins, leukotrienes and thromboxanes

Conaway

9/04/08

CE06

JAK-STAT signaling in endocrine tissues

O’Brien

9/09/08

CE07

 Microarray design methods

McGehee

9/11/08

CE08

Microarray analytical methods

Nagarajan

9/16/08

CE09

Practical microarray analysis

Nagarajan

9/18/08

CE10

Microarray analysis instruction

Nagarajan

9/23/08

CE11

Nuclear receptor superfamily signaling

MacLeod

9/25/08

CE12

Nuclear receptor signaling/co-regulation

MacLeod

9/30/08

 

Exam #1 - 110 points

 

10/02/08

CE13

General principles involved in identifying G-Protein coupled receptors 

Suva

10/7/08

CE14

Receptor purification, and gene structure, induction

Suva

10/9/08

CE15

G-protein coupled receptor desensitization

Jones

10/14/08

CE16

Endocrine control of calcium metabolism

Jilka

10/16/08

CE17

Hormonal regulation of uterine function

Simmen

10/21/08

CE18

Hormonal regulation of ovarian function

Gaddy

10/23/08

CE19

Hormonal control of male reproduction

Diekman

10/28/08

CE20

Neuroendocrine hormones and regulation

Childs

10/30/08

 

Attend Career Day and Development-NO Class

 

11/04/08

CE21

Regulation and effects of menopause

Gaddy

11/06/08

 

Exam #2 - 90 points

 

11/11/08

 

Veterans Day HOLIDAY-No Class

 

11/13/08

CE22

Hormonal control of GI function

Chowdhury

11/18/08

CE23

Diabetes/metabolic syndrome

Bunn

11/20/08

 

Student Presentations
Reports Due - 30 points

Gaddy/Nagarajan

11/25/08

CE24

Obesity

Bunn

11/27/08

 

THANKSGIVING-No class

 

12/2/08

CE25

Endocrine/Metabolism Integration I

Conaway

12/04/08

CE26

Endocrine/Metabolism Integration II

Conaway

12/09/08

CE27

Strategies in Endocrine therapy development

Suva

12/11/08

CE28

Cancer treatment effects on endocrine Tissues

Suva

12/16/08

CE29

Clinical endocrine therapies: primary and secondary target tissue effects

Gaddy

12/18/08

 

Exam #3 - 80 points

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Aug 4, 2008

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