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Student NewsBiny Joseph will defend his dissertation titled "Loss of K+ Channels in the Cerebral Circulation of Hypertensive Rats: Membrane Associated Proteins and Myogenic Tone" Tuesday, July 14th, 2009 (10:00 – 11:00 a.m. ) in the Rayford Auditorium. Congratulations to Sujay Kharade, who was awarded an American Heart Association Predoctoral Fellowship for two years, beginning July 2009, from the South Central Affiliate of the AHA. The title of Sujay's proposal was "Mechanisms of Vascular L-Type Calcium Channel Upregulation in Hypertension". Sujay also was a runner-up this year in the graduate student competition of the Cardiovascular Pharmacology Division of ASPET. Venkata Bhogaraju will defend his disseration "Characterization of Cu, Zn Superoxide Dismutase In Vivo: Zn-Deficient SOD1 as a Potential Neurotoxic Species in Amyotrophic Lateral Sclerosis" at 1:00 pm on January 16, 2009 in the Rayford Auditorum. Congratulations to Sarah White, Ph.D. for successfully defending her dissertation "Effects of methamphetamine on pregnant rats and their litters in the presence and absence of anti-methamphetamine monoclonal antibody therapy"! Congratulations to Shankar Munusamy, Ph.D. for successfully defending his dissertation "Involvement of Oxidants and Mitochondrial Dysfuntion in the Pathogenesis of Hyperglycemia-induced Renal Injury" on Dec. 5. Dr. Munusamy will be going to the University of Mississippi Medical Center for a postdoc in Dr. John Hall's lab. Good luck Shankar!! Congratulations to Jonanthan Hubbard, Ph.D., who successfully defended his dissertation "Monoclonal Antibodies as Protective Medications for Drug Abuse During Pregnancy" on Dec. 4! Mark The Dates:
Congratulations to Kathryn Seely (Interdisciplinary Toxicology Program) for winning the Best Poster award and a travel award to attend the Society of Neuroscience meeting in DC Nov. 3, 2008 from the Arkansas Chapeter of the Society of Neuroscience! Congratulations to Biny Joseph (Interdisciplinary Toxicology Program) for winning the Junior Scientist Graduate Student competition in Cardiovascular Pharmacology sponsored by ASPET at Experimental Biology, April 8, 2008 in San Diego. Biny's presentation was entitled “Shaker Kv1 channel-MAGUK complexes are down-regulated in cerebral arteries of hypertensive rats”. Congratulations go out to Venkata Bhogaraju (Pharmacology Program) for placing 2nd in the ASPET-sponsored Best Abstract Competition in Neuropharmacology at Experimental Biology, April 7, 2008 in San Diego. His poster presentation was entitled "Biochemical characterization of G93A mutant human Cu,Zn superoxide dismutase purified from transgenic rat spinal cord". Shankar Munusamy, Pharmacology Graduate Student, received the Chair's Fund Award at the Gordon Conference on Oxygen Radicals in Ventura, California in March 2008. Shankar presented a poster entitled “Protective role of manganese superoxide dismutase against hyperglycemia-induced mitochondrial dysfunction and renal cell injury”. Congratulations Shankar! We had a great showing on Student Research Day! Special congratulations goes out to Jon Hubbard, MD/PhD candidate in pharmacology, for winning a 1st place $1,000 travel award from the Graduate School for his abstract “Gestation stage-dependent changes in monoclonal antibody pharmacokinetics and function during rat pregnancy” and Sarah White, PhD candidate in pharmacology for winning a $500 UAMS IDeA Networks of Biomedical Research Excellence (INBRE) travel award for her abstract “(+) Methamphetamine pharmacokinetics in timed-pregnant rats during early- and late-stage pregnancy”. Both students are the lab of Dr. Michael Owens. Congratulations to Brian Donahower (Pharmacology) and Zabeena Shaik (Pharmacology with Pharmaceutical Sciences Track) for successfully defending their dissertations in December 2007. Dr. Donahower's dissertation was entitled “Examination of vascular endothelial growth factor (VEGF) in a mouse model of acetaminophen toxicity”. Dr. Shaik's dissertation was entitled “Protective role of protein kinase B/AKT against mitochondrial dysfunction and cell death in nephrotoxicant injured renal cells”. We wish both of them the best of luck! Congratulations to January Baumgardner (Interdisciplinary Toxicology) for defending her dissertation on October 5, 2007 entitled "Effects of diet and nutritional status on progression of fatty liver disease in rats fed via total enteral nutrition". Dr. Baumgardner worked in the laboratory of Dr. Martin Ronis. Congratulations to Rajesh Vadlapatla (now Dr. Vadlapatla) for defending his Ph.D. dissertation on July 23, 2007 entitled "Drug-Organic Electrolyte Complexes as Controlled Release Systems". Rajesh is the first Pharmaceutical Sciences Track graduate in the Pharmacology Program and his advisor was Dr. Cherng-ju Kim. Best of luck to you Dr. Vadlapatla! Congratulation to Nichole Dowdy-Sanders, a graduate student in the Interdisciplinary Toxicology Program! She has received a travel award from American Society of Pharmacology and Experimental Therapeutics to attend the Experimental Biology meeting in April, 2007. Nichole's abstract “Effect of d-amphetamine-SO4 on learning in Ts65Dn, a murine model of Down syndrome, at 20-months of age” was also chosen for a press release. Rohit Singhal, an INTOX graduate student working with Dr. Ronis, was recently awarded not one but three travel awards! One is to attend the Society of Toxicology meeting in March, 2007 and the other two: the Colgate Palmolive Award for Student Research Training in Alternative Methods and the Technology Transfer Award from the South Central Chapter of the Society of Toxicology will support Rohit to travel to the lab of his choice to learn new techniques. Rohit has chosen to visit Dr. Stephan Safe's lab at Texas A&M to learn Fluorescence Resonance Energy Transfer (FRET) analysis. The Department made a great showing at the 2007 Student Research Days April 4-5 event. A special congratulations to Shankar Munusamy (Pharmacology) and Zabeena Shaik (Pharmaceutical Sciences Track) for their research awards! Eric Peterson, Ph.D. (postdoctoral fellow) won second place in the fellow category with his research titled Preclinical Testing of a High Affinity Single Chain Antibody Against (+)-Methamphetamine (METH). Our graduate student presenters were: Rohit Singhal Estrogenic Status Modulates DMBA-Mediated Hepatic Gene Expression: A Mechanistic Approach Using Microarrays; Nichole Dowdy-Sanders Effect of d-Amphetamine (SO4) on Learning in Ts65Dn, a Murine Model of Down Syndrome, at 21-Months of Age; Shankar Munusamy Overexpression of Manganese Superoxide Dismutase in Renal Proximal Tubular Cells Protects Against Hyperglycemia-Induced Renal Injury; Lalit Oberoi UV-Visible Spectroscopy and Inotropic Effects of Organic and Aqueous Extracts of Terminalia Arjuna Bark on Adult Ventricular Myocytes; Brian Donahower Evaluation of VEGF as a Treatment for Acetaminophen Toxicity; Biny Joseph Down Regulation of Shaker-Type Voltage-Gated Potassium Channels in Cerebral Arteries During Hypertension; Dinesh Hirenallur-Shanthappa Upregulation of Ca2+ Channels in Pulmonary Microvessels of Neonatal Piglets with Hypoxia-Induced Pulmonary Hypertension; Swapnil Sonkusare Expression of a B2 Subunit Mutant Alters Ca2+ Currents in HLp1 Cells; Kathryn Seely Treatment with CB2 Specific Cannabinoids Modulate Expression of Inflammatory Cytokine/Chemokine mRNA in Spinal Cords of G93A-SOD1 Mice; Sarah White Pharmacokinetics and Postnatal Effects Following Acute Methamphetamine Administration to Rats during Late-Stage Pregnancy; Himani Vejandla Hydrogen Peroxide and 4-Hydroxynonenal Downregulate L-Type Calcium Channel Expression in Rat Aortic Vascular Smooth Muscle Cells; and Zabeena Shaik Protein Kinase B/Akt Activation Improves Oxidative Phosphorylation in Injured Renal Cells.
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