Pathology Research

In addition to outstanding clinical services and academics, the Department of Pathology supports active research programs funded by NIH and other extramural sources.

Steven Post, Ph.D
Director, Experimental Pathology Division

Mission:
To provide the Department of Pathology with a recognized research program that furthers our understanding of the pathogenesis, diagnosis and treatment of disease.

Objectives:
*To integrate clinical and basic research efforts within the Department of Pathology
*To facilitate intra and inter departmental collaborations

Current Experimental Pathology Research Projects:
Kumuda Das, Ph.D: Oxidative stress and redox control of gene expression, Redox control of cell cycle regulation, and mechanisms of redox-cycling of anthracycline class of antitumor agents.
Kathleen Eisenach, Ph.D: Tuberculosis diagnosis, epidemiology and pathogenesis.
Randy Haun, Ph.D: Tumor markers, metastasis, proteases, gene expression
Leah Hennings, DVM, Ph.D: Mediators of inflammation and their relationship to neoplasia, nutrition and dietary supplements, and transgenic animals as models of disease
Sarah Johnson, Ph.D: Reactive oxygen species and mechanisms of chemoresistance
Behjatolah Karbassi, Ph.D: Tumor glycobiology and metastasis, and tumor immunotherapy
Thomas Kelly, Ph.D: Breast cancer
Thomas Kieber-Emmons, Ph.D: Cancer immunology and glycobiology
Steven Post, Ph.D: Cardiovascular/inflammation
Sue Theus, Ph.D: Mycobacterium tuberculosis and how it interacts with immune cells

Current Anatomic Pathology Research Projects:
Harry Brown, MD: Clinicopathological correlations of ocular disease; mechanism(s) of retinal injury in child abuse
Chun-Yang Fan, MD, Ph.D: Genetic and epigenetic (promoter methylation) alterations in head and neck cancer
Murat Gokden, MD: Neuropathology and Cytopathology
Neriman Gokden, MD: Renal cell carcinomas
Kim Hiatt, MD: Dermatopathology
Soheila Korourian, MD: Clinicopathological correlations of breast cancer and pathophysiology of ductal carcinoma in situ
Laura Lamps, MD: Gastrointestinal and hepatic disease
Bruce Smoller, MD: Cutaneous lymphomas and leukemias, immunopathology

Current Clinical Pathology Research Projects:
William Bellamy, RPh, Ph.D: Multiple Myeloma; Myelodyslastic syndromes; Non-hodgkins lymphomas; Expression of angiogenic factors in hematopoietic neoplasms; Antineoplastic drug resistance
Joshua Bornhorst, Ph.D: Assay Interferences, Immunoassays, Alpha 1-Antitrypsin Deficiency, Laboratory Automation
Michele Fox, MD: Improving stem cell transplantation
Mayumi Nakagawa, MD, PhD: Studying cell-mediated immunity to human papillomaviruses (HPV) and developing HPV therapeutic vaccines
Steven Schichman, MD, Ph.D: Prognostic markers in chronic lymphocytic leukemia, pharmacogenomics and genome wide association studies in support of VA Cooperative Studies Program.

Core Labs:

 
Leah Hennings, DVM, PhD
Director
The Experimental Pathology Shared Resource Laboratory is a non-profit laboratory that provides all UAMS researchers with centralized, comprehensive histological services.

Marwan Yared, MD
Director
The UAMS Tissue bank is an institution-wide tissue procurement facility, coordinating and overseeing the donation, processing, storage, and dissemination of tissue specimens and related data.

Research Links:

Office of Research and Sponsored Programs

PubMed

UAMS IRB

UAMS Research Support Center

UAMS Research Calendar