Tammy L. Kielian, Ph.D. - Faculty - Department of Neurobiology and Developmental Sciences - University of Arkansas for Medical Sciences


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Tammy L. Kielian, Ph.D.
Title Dr. Kielian has moved her laboratory to the University of Nebraska Medical Center in Omaha, NE. Click to find her new address. PhD Microbiology, University of Kansas Medical Center, Kansas City Major Interests Immune responses in the CNS: The roles of microglia and astrocytes in CNS infectious disease; functions of Toll-like receptors (TLRs) in bacterial recognition by glia; interface between TLRs and adaptive immunity in CNS bacterial infections; effects of inflammation on gap junction communication in glial cells. Email: tkielian@unmc.edu Address: University of Nebraska Medical Center Department of Pathology and Microbiology 983135 Nebraska Medical Center Omaha, NE 68198-3135 Phone: (402) 559-8002 Fax: (402) 559-4077

Selected Publications

1. Kielian, T., Esen, N., and Bearden, E.D. Toll-like receptor 2 (TLR2) is pivotal for recognition of S. aureus peptidoglycan but not intact bacteria by microglia, Glia, 49:567-576, 2005.

2. Kielian, T., Haney, A., Mayes, P.M., Garg, S., and Esen N. Toll-like receptor 2 (TLR2) modulates the proinflammatory milieu in S. aureus-induced brain abscess, Infect. Immun., 73:7428-7435, 2005.

3. Esen, N. and Kielian, T. Central role for MyD88 in the responses of microglia to pathogen-associated molecular patterns (PAMPs), J. Immunol., 176:6802-6811, 2006.

4. Phulwani, N.K., Feinstein, D.L., Gavrilyuk, V., Akar, C., and Kielian T. 15-deoxy-∆12,14-prostaglandin J2 (15d-PGJ2) and ciglitazone modulate astrocyte activation through PPAR-γ-independent pathways, J. Neurochem., 99:1389-1402, 2006.

5. Esen, N., Shuffield, D., Syed, M. Md., and Kielian, T. Modulation of connexin expression and gap junction communication by the gram-positive pathogen S. aureus, Glia, 55:104-117, 2007.

6. Kielian, T., Phulwani, N.K., Esen, N., Syed, M.Md., Haney, A.C., McCastlain, K., and Johnson J. MyD88-dependent signals are essential for the host immune response in experimental brain abscess, J. Immunol., 178:4528-4537, 2007.

Link to Dr. Kielian's PubMed publications

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