The Department of Microbiology and Immunology occupies 20,000 square feet of modern, state-of-the-art research space in the Biomedical Research Building on the University of Arkansas for Medical Science campus. The Department is fully equipped with all the instrumentation necessary to conduct cutting edge research in microbiology, genetics, cell  biology and immunology. The Department houses and maintains the campus core facilities in DNA sequencing and flow cytometry and cell sorting. There is also easy access on campus to a microarray core facility and confocal microscopy. The Department also operates a fully equipped Level 3 Biologic Containment Unit in which basic bench work as well as animal studies can be conducted.

The research community on campus is serviced by a dedicated computer network designed to link and support all researchers  including desktop support, a dedicated research intranet and internet access, including Internet II. Every laboratory in the Department of Microbiology and Immunology has multiple computer ports. In addition to multiple computers in virtually every laboratory, designated computers, scanners, and printers are available for student use. The Department conference room is equipped with a computer projection system fully linked to the campus network as are all of the major lecture and seminar facilities on campus.

Library support includes holdings to the major medical and basic science journals including access to many online journals as well as a literature retrieval system for all Medline journals with desktop access through the campus network.

Students also benefit from the collaborative relationship between UAMS and other research facilities on or near the medical campus: The John L. McClellan Veterans Administration Hospital, the Arkansas Cancer Research Center, the John F. Reynold's Geriatric Institute, Arkansas Children's Hospital, Jones Eye Institute and the National Center for Toxicological Research. Several department faculty have laboratories in these facilities.

Recently, a new 6 story research building and a 10 story Jackson T. Stephens Spine and Neurological Science Institute building have been completed, thus continuing the dramatic expansion of research facilities on this campus.