Klimberg Named Inaugural Chair in Breast Surgical Oncology

What began as a friendship has developed into a gift that will benefit breast cancer research for countless years to come.

“You hold a very special place in the heart of the Tenenbaum family,” Judy Tenenbaum said to V. Suzanne Klimberg, M.D., at the Jan. 23 ceremony naming Klimberg inaugural recipient of the Muriel Balsam Kohn Chair in Breast Surgical Oncology at the University of Arkansas for Medical Sciences (UAMS).

“UAMS is a much better place because of the work Suzanne has done and continues to do for breast cancer patients everywhere,” Tenenbaum said.

Klimberg is chief of the Division of Breast Surgical Oncology at UAMS and a professor in the Departments of Surgery and Pathology. She also is director of the Breast Cancer Program at the UAMS Winthrop P. Rockefeller Cancer Institute as well as director of Breast Fellowship in Diseases of the Breast at UAMS.

“Dr. Klimberg is a champion for breast cancer patients and survivors,” said UAMS Chancellor I. Dodd Wilson, M.D. “She fights tirelessly to ease the burden of this disease, which affects so many of our mothers, sisters, wives and daughters. We honor her today for her compassionate patient care and her pioneering research that has changed the way we look at breast cancer.”

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V. Suzanne Klimberg, M.D., (center) with Judy Tenenbaum and Harold Tenenbaum.

Study Reports Reversal of Alzheimer’s Symptoms Within Minutes

An extraordinary new scientific study, which for the first time documents marked improvement in Alzheimer’s disease within minutes of administration of a therapeutic molecule, has just been published in the Journal of Neuroinflammation. 

This new study highlights the importance of certain soluble proteins, called cytokines, in Alzheimer’s disease. The study focuses on one of these cytokines, tumor necrosis factor-alpha(TNF), a critical component of the brain’s immune system. Normally, TNF finely regulates the transmission of neural impulses in the brain. The authors hypothesized that elevated levels of TNF in Alzheimer’s disease interfere with this regulation. To reduce elevated TNF, the authors gave patients an injection of an anti-TNF therapeutic called etanercept. Excess TNF-alpha has been documented in the cerebrospinal fluid of patients with Alzheimer’s.

The new study documents a dramatic and unprecedented therapeutic effect in an Alzheimer’s patient: improvement within minutes following delivery of perispinal etanercept, which is etanercept given by injection in the spine. Etanercept (trade name Enbrel) binds and inactivates excess TNF. Etanercept is FDA approved to treat a number of immune-mediated disorders and is used off label in the study. 

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