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CRC Core Laboratories
The CRC
Core Laboratories are available to support approved CRC protocols.
Protocols that only require the core laboratories may be considered by the SAC. Please contact
Subramanian Ranganathan, PhD, or
Cindy Henrich,
MS, for questions on how to use these core
laboratories. Please contact
Dr. Ranganathan for specialized support of existing or contemplated CRC
projects that are not covered by these core laboratories. The lab
personnel meet with investigators during the implementation meeting to
specify how the samples are to be processed and what tests are to be carried
out.
The Core
Laboratories are comprised of two functioning labs. They offer customized
specimen processing services including:
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Set up
blood collection tubes for OGT, IVGT and other procedures
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Centrifugation to separate serum or plasma for storage and analysis
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Isolation of different cell types from whole blood
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Isolation of DNA from whole blood or leukocytes
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Glucose measurement using YSI glucose analyzer
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Short
term storage of specimens at -20o or -80o C
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Preparation for sending specimens to LabCorp for various tests such as
Hepatic function test, Glucose, Electrolyte, HbA1c, Lipid panel,
Metabolic panes, and Creatinine.
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Additionally, the CRC Core Lab offers various assays for the
investigators. We can assay several hormones, peptides and other blood
components using commercially available ELISA kits. The lab employs state of
the art immuno-chemiluminometric
techniques
for the assay of insulin, C-peptide and proinsulin. We also offer
measurement of deuterium oxide for the assessment of total body water.
The Core Lab assists the
investigator in the mounting and freezing of human muscle tissue
obtained by the biopsy technique.
The Core Lab Director must approve specialty procedures
prior to submission of the CRC application.
If you would like more
information or you feel that we might be of service to you, please contact
Dr.
Subramanian Ranganathan, CRC Core Lab Manager, at 501-526-4679.
The Lab staff can be reached at 501-526-7784.
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