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Department of Internal Medicine
Faculty Publications 2004-2008

Division of Cardiovascular Medicine

Agarwal N, You H, Liu Y, Chiriva-Internati M, Bremner J, Garg T, Grizzi F, Krishna Prasad C, Mehta JL, Hermonat PL. Generation of recombinant skin in vitro by adeno associated virus type 2 vector transduction. Tissue Engineering 2004; 10:1707-15.

Amani F, Smith ES. Atrial fibrillation: rate versus rhythm control. J Ark Med Soc 2005;102:110-2.

Aude YW, Mehta JL. Do we need continuous ECG monitoring in patients transferred for primary angioplasty? (Editorial) European Heart Journal 2005;27:249-50.

Aude YW, Lamas GA, Lopez-Jimenez F, Lieberman EH, Almon M, Hansen M, Rojas G, Agatston AS, Hennekens CH. A randomized trial comparing the National Cholesterol Education Program Step 2 Diet to a diet lower in carbohydrates and higher in protein and monounsaturated fat (The South Beach Diet Study). Arch Intern Med 2004; 164:2141-6.

Aude YW, Mego P, Mehta JL. Metabolic syndrome: dietary interventions. Current Opinion in Cardiology 2004; 19:473-9.

Bagwe S, Sachdeva R, Mehta JL.  High-risk acute coronary syndrome patient and cardiac biomarkers in the emergency department: where do we stand?  Eur Heart J 2007; 28(9):1043-4. Editorial.

Bansal D, Chahoud G, Ison K, Gupta E, Montgomery M, Garza L, Mehta JL. Pleuropericarditis and pericardial tamponade associated with inflammatory bowel disease. Journal of the Arkansas Medical Society 2005;102:16-9.

Bansal D, Gaddam V, Aude YW, Bissett J, Fahdi I, Garza L, Joseph J, Molavi B, Pai BV, Sinha A, Smith ES, Mehta JL. Trends in the care of patients with acute myocardial infarction at a university-affiliated VA medical center. Journal of Cardiovascular Pharmacology and Therapeutics 2005; 10: 39-44.

Bansal D, Chahoud G, Smith ES, Mehta JL.  Prevention of heart failure. Curr Opin Cardiol 2006;21(5):510-6.

Bansal D, Chahoud G and Mehta JL. Heart failure prevention. Current Opinion in Cardiology 2006; 21(5):510-6.

Bansal D, Eigenbrodt M, Gupta E, Mehta JL.  Traditional risk factors and acute myocardial infarction in patients hospitalized with cocaine-associated chest pain.  Clin Cardiol 2007; 5;30(6):290-294.

Bloomfield HE, Nelson DB, van Ryn M, Neil BJ, Koets NJ, Basile JN, Samaha FE, Kaul R, Mehta JL, Bouland D. A trial of education, prompts, and opinion leaders to improve prescription of lipid modifying therapy by primary care physicians for patients with ischemic heart disease. Quality and Safety in Health Care 2005; 14:258-63.

Boucher A, Lu D, Burgess SC, Télémaque-Potts S, Jensen MV, Mulder H, Wang MY, Unger RH, Sherry AD and Newgard CB. Biochemical mechanism of lipid-induced impairment of glucose-stimulated insulin secretion and reversal with a malate analogue. J Biol Chem 2004; 279:27263-71.

Brenner B, Harney JT, Ahmed BA, Jeffus BC, Unal R, Mehta JL, Kilic F.  Plasma serotonin levels and the platelet serotonin transporter. J Neurochem 2007; 102(1)206-15.

Burrows DR, Smith ES.  Pericarditis: guidelines and management. J Ark Med Soc 2006;103(4):89-90.

Camp TM, Aru GM, Hayden MR, Mehta JL, Tyagi SC. Doxycycline ameliorates ischemic and border-zone remodeling and endothelial dysfunction after myocardial infarction in rats. Journal of Heart and Lung Transplantation 2004; 23:729-36.

Chahoud G, Aude YW, Mehta JL. Dietary Recommendations in the Prevention and Treatment of Coronary Heart Disease: Do We Have the Ideal Diet Yet?. Am J Cardiol 2004; 94:1260-7.

Chahoud G, Mehta JL. Heparin induced thrombocytopenia and thrombosis. Clinical Cardiology 2004; 27:514Chen J, Li D; Schafer R, Mehta JL.
Cross-talk between dyslipidemia and renin-angiotensin system and the role of lox-1 and MAPK in atherogenesis: Studies with the combined use of rosuvastatin and candesartan. Atherosclerosis 2006;184(2):295-301.

Chen J, Mehta JL, Haider N, Zhang X, Narula J, Li D. Role of caspases in ox-LDL-Induced apoptotic cascade in human coronary artery endothelial cells. Circulation Research 2004: 94:370-6.

Chen J, Mehta JL. Role of oxidative stress in coronary heart disease. Indian Heart Journal 2004; 56:163-73.

Chen J, Li D, Schaefer RF, Mehta JL. Inhibitory effect of candesartan and rosuvastatin on CD40 and MMPs expression in Apo-E knockout mice: Novel insights into the role of RAS and dyslipidemia in atherogenesis. Journal of Cardiovascular Pharmacology 2004; 44:446-52.

Chen J, Li D, Zhang X, Mehta JL. TNF-?-induced apoptosis of human coronary artery endothelial cells: modulation by the PPAR-? ligand pioglitazone. Journal of Cardiovascular Pharmacology and Therapeutics 2004; 9:35-41.

Chen J, Li D; Schafer R, Mehta JL. Cross-talk between dyslipidemia and renin-angiotensin system and the role of lox-1 and MAPK in atherogenesis: Studies with the combined use of rosuvastatin and candesartan. Atherosclerosis 2005; 184(2):295-301.

Chen J, Liu H, Hermonat PL, Mehta JL. Molecular Dissection of Human LOX-1 Promoter:  Nucleotides and Transcription Factors Requirement During Transactivation. Journal of the American College of Cardiology 2006;47:340A.

Chen J, Liu H, Liu Y, Hermonat PL, Mehta JL. Combination of aspirin and Pravastatin dramatically reduces oxidative stress and the expression of LOX-1 and adhesion molecules:  Novel insight into the mechanism of action of aspirin and statins. Journal of the American College of Cardiology 2006;47:340A.

Chen J, Liu Y, Liu H, Hermonat PL, Mehta JL. Oxidized-LDL receptor LOX-1 transcriptional regulation by Oct-1 in human endothelial cells:  Implications for atherosclerosis. Biochemical Journal 2006;393: 255-65.

Chen J, Mehta JL. Interaction of oxidized low-density lipoprotein and the renin-angiotensin system in coronary artery disease. Current Hypertension Reports. 2006;8:139-43.

Chen J, Mehta JL.  Angiotensin II-mediated oxidative stress and procollagen-1 expression in cardiac fibroblasts: blockade by pravastatin and pioglitazone.  AJ Physiol: Heart Circ Physiol 2006;291(4):H1738-45.

Chen K, Chen J, Li D, Zhang X, Mehta JL. Angiotensin II regulation of collagen type-I expression in cardiac fibroblasts: Modulation by the PPAR-? Ligand Pioglitazone. Hypertension 2004; 44:1-7.

Chen K, Li D, Zhang X, Hermonat PL, Mehta JL. Anoxia-reoxygenation stimulates collagen type-I and MMP-1 expression in cardiac fibroblasts: Modulation by the PPAR-? ligand pioglitazone. Journal of Cardiovascular Pharmacology 2004; 44:682-7.

Chen K, Mehta JL, Li D, Joseph L, Joseph J. The TGF-? receptor endoglin is expressed in cardiac fibroblasts pro-fibrogenic actions of angiotensin II. Circulation Research 2004; 95:1167-73.
Chen K, Liu Y, Chen J, Li D, Hermonat PL, Sawamura T, Mehta JL. Adhesion molecule expression in fibroblasts: Alteration in fibroblast biology following transfection with LOX-1 plasmids. Hypertension 2005;46:622-7.

Chen X, Zhang X, Kubo H, Harris DM, Mills GD, Moyer J, Berretta R, Télémaque-Potts S, Marsh JD and Houser SR.  Ca2+ Influx-induced sarcoplasmic reticulum Ca2+ overload causes mitochondrial-dependent apoptosis in ventricular myocytes. Circ Res 2005;97:1009-17.

Chiriva-Internati M, Grizzi F, Jumper CA, Cobos E, Hermonat PL, Frezza EE.   Immunological treatment of liver tumors.  World J Gastroenterol 2005; 14(11):6571-6.

Cola C, R Almeida M, Li D, Romeo F, Mehta JL. Regulatory role of endothelium in the expression of genes affecting arterial calcification. Biochemical Biophysical Research Communications 2004; 320:424-7.

Dandapat A, Chen J, Hu CP, Liu Y, Li D, Thomas M, Hermonat PL, Sawamura, Mehta JL. LOX-1 ablation reduces atherosclerosis. American Heart Association Scientific Sessions 2006 Annual Meeting, November 12-15, Chicago, IL. Circ 2006; 114: II-254a.

Dandapat A, Liu Y, Chen J,  Hu CP, Li D, Hermonat PL, Mehta JL.  Delivery of angiotensin II type 2 receptor cDNA with adeno-associated virus type 2 by intravenous route decreases atherosclerosis in the LDLR knockout mice fed with high cholesterol diet. American Heart Association Scientific Sessions 2006 Annual Meeting, November 12-15, Chicago, IL. Circ 2006; 114: II-214a.

Darpan BD, Gaddam V, Aude YW, Bissett J, Fahdi I, Garza L, Joseph J, Molavi B, Pai B, Sinha A, Smith E, Mehta JL. Trends in the care of patients with acute myocardial infarction at a University-affiliated VA Medical Center. J Cardiovasc Pharmacol Therapeut 2005; 10:39-44.


De Las Casas L E, Gokden M, Mukunyadzi, White P, Baker S J, Hermonat P L, Hong Y, Korourian S, Malka S F, Miranda R N. “A morphologic and statistical comparative study of small cell carcinoma and non-Hodgkin’s lymphoma in fine needle aspiration biopsy material from lymph nodes. Diagnostic Cytopathology 31: 229-234, 2004.

De Las Casas LE, Gokden M, Baker SJ, Korourian S, Hermonat PL, You H, Miranda RN, Shalkham JE, O'Brien LA, Mukunyadzi P. Malignant melanoma metastatic to the liver. A cytomorphologic comparative study to identify reproducible diagnostic criteria. Acta Cytol 2004; 48:32-8.

De S, Sharma R, Trigwell S, Laska B, Ali N, Mazumder MK, Mehta JL. Plasma treatment of polyurethane coatings for improved endothelial cell growth and adhesion. Journal of Biomaterials Science, Polymer Edition, 2005;16: 973-989.

Eigenbrodt M, Bursac Z, Eigenbrodt EP, Couper DJ, Trace RE, Mehta JL. Mathematical estimation of the potential effect of vascular remodeling/ectasia on B-mode ultrasound intima-media thickness. Quarterly Journal of Medicine 2004; 97:729-37.

Eigenbrodt  ML, Bursac  Z,  Rose  KM,  Couper  DJ, Tracy RE, Evans  GW,   Brancati  F, Mehta JL. Common carotid arterial (CCA) interadventitial distance (diameter) as an indicator of the damaging effects of age and atherosclerosis, a cross-sectional study of the Atherosclerosis Risk in Community Cohort Limited Access Data (ARICLAD), 1987-89.  Cardiovascular Ultrasound. 2006;4:1.

Eigenbrodt ML, Sukhija R, Rose KM, Tracy RE, Couper DJ, Evans GW, Bursac Z, Mehta JL.  Common carotid artery wall thickness and external diameter as predictors of prevalent and incident cardiac events in a large population study. Cardiovasc Ultrasound 2007;5:11.

Fahdi IE, Gaddam V, Saucedo JF, Kishan CV, Vyas K, Deneke MG et al. Bradycardia during therapy for multiple myeloma with thalidomide. American Journal of Cardiology 2004; 93(8):1052-1055.

Fahdi IE, Molavi B, Mehta JL. The ratio of triglyceride to high-density lipoprotein is an independent risk factor for angiographic coronary atherosclerosis in patients with metabolic syndrome. Circulation 2004; 25: 109:16(P77).

Fahdi IE, Saucedo JF, Hennebry T, Ghani M, Sadanandan S, Garza L. Incidence and time course of thrombocytopenia with abciximab and eptifibatide in patients undergoing percutaneous coronary intervention. American Journal of Cardiology 2004; 93:453-455.

Fan QI, Vanderpool KM, Chung H-S, Marsh JD. The L-type calcium channel alpha 1C subunit undergoes extensive, uncoordinated alternative splicing.  Mol Cell Biochem 2005; 269(1-2); 153-63.

Golden KL, Marsh JD, Jiang Y, Moulden J. Gonadectomy alters myosin heavy chain composition in isolated cardiac myocytes. Endocrine 2004; 24(2):137-40.

Golden KL, Marsh JD, Jiang Y. Testosterone regulates mRNA levels of calcium regulatory proteins in cardiac myocytes. Horm Metab Res 2004; 36(4): 197-202.

Golden KL, Marsh JD, Jiang Y, Moulden J.  Acute actions of testosterone on contractile function of isolated rat ventricular myocytes.  Eur J Endocrinol; 152(3):470-83, 2005.

Grizzi F, Chiriva-Internati M, Franceschini B, Bumm K, Colombo P, Ciccarelli M, Donetti E, Gagliano N, Hermonat PL, Bright RK, Gioia M, Dioguardi N, Kast WM. Sperm protein 17 is expressed in human somatic ciliated epithelia. J Histochem Cytochem 2004; 52:549-54.

Grizzi F, Franceschini B, Hermonat PL, Liu Y, Chiriva-Internati M. Some remarks on the somatic expression of sperm protein 17. Int J Cancer 2004; 10 (111):972-3.

Grizzi F, Russo C, Portinaro N, Hermonat PL, Chiriva-Internati M. Complexity and cancer. Gastroenterology 2004; 126:630-1.

Hamilton KL, Quindry JC, French JP, Staib J, Hughes J, Mehta JL, Powers SK. MnSOD antisense treatment and exercise-induced protection against arrhythmias. Free Radical Biology & Medicine 2004; 37:1360–8.

Hayes E, Mehta P, Mehta JL. Depression in heart disease – A plea for help! (Editorial) Indian Heart Journal 2005;57:360-3.

Hauer-Jensen M, Fort C, Mehta JL, Fink LM. Influence of statins on postoperative wound complications after inguinal or ventral herniorrhaphy. Hernia 2006;10:48-52.

Hermonat PL, Mehta JL. Potential of gene therapy for myocardial ischemia. Curr Opin Cardiol 2004;19:517-23.

Hermonat PL, You H, Chiriva-Internati CM, Liu Y.   Analysis of adeno-associated virus and HPV interaction.  Methods Mol Med 2005;119:397-409.

Hermonat PL, Li D, Yang B, Mehta JL.  Mechanism of action and delivery possibilities for TGFbeta1 in the treatment of myocardial ischemia. Cardiovasc Res 2007;74(2):235-43.

Hermonat PL, editor. Cancer and Gene Therapy. 2007.

Hinagata JI, Kakutani M, Fujii T, Naruko T, Inoue N, Fujita Y, Mehta JL, Ueda M, Sawamura T. Oxidized LDL receptor LOX-1 is involved in neointimal hyperplasia after balloon arterial injury in a rat model. Cardiovascular Research 2005;69:263-71.

Hu CP, Chen J, Dandapat A, Li D, Liu Y, Hermonat PL, Mehta JL. Targeted deletion of LOX-1 ameliorates myocardial ischemia-reperfusion injury in mice, reduces inflammation and expression of MMPs. American Heart Association Scientific Sessions 2006 Annual Meeting, November 12-15, Chicago, IL. Circ. 2006; 114: II-157a.

Huang H, Wang H, Wu ZQ, You CX, Luo RC, Yong L, Hermonat PL.  Effects of two different antigen-loading methods on the activity of dendritic cell vaccine for colorectal carcinoma cell inhibition in vitro]  Nan Fang Yi Ke Da Xue Xue Bao 2007 ;27(4):492-5. Chinese.

Hughes B, Chahoud G, Mehta JL. Aortic stenosis:  Is it simply a degenerative process or an active atherosclerotic process? (Editorial) Clinical Cardiology 2005; 28: 111-4.

Joseph J,  Rimawi A, Mehta P, Cottler-Fox M,  Sinha A, Singh BK,  Pacheco R, Smith ESMehta JL. Safety and effectiveness of granulocyte-colony stimulating factor in mobilizing stem cells and improving cytokine profile in advanced chronic heart failure. American Journal of Cardiology 2006;97:681-4.

Khan Q, Mehta JL. Relevance of platelet-independent effects of aspirin in its salutary effect in atherosclerosis-related events. Journal of Atherosclerosis and Thrombosis 2005;12:185-90.

Khan Q, Sachdeva R, Mehta JL. Hyperglycemia predicts failure in percutaneous intervention of coronary chronic total occlusion.  Southern Society for Clinical Investigation meetings, New Orleans, LA, February, 2007;50:S195a.

Lennon S, Quindry JC, Hamilton KL, French J, Staib J, Mehta JL, Powers SK. Loss of exercise-induced cardioprotection following cessation of exercise. Journal of Applied Physiology 2004 96:1299-305.

Lennon S, Quindry JC, Hamilton KL, French J, Staib J, Mehta JL, Powers SK. Elevated MnSOD is not required for exercise-induced cardioprotection against myocardial stunning. American Journal of Physiology 2004;287:H975-80.

Leonardi M, Bissett J.  Prevention of atrial fibrillation. Curr Opin Cardiol 2005;20:417-23. 

Li D, Chen K, Sinha N, Zhang X, Sinha AK, Romeo F, Mehta JL. The effects of  ligand pioglitazone on platelet aggregation and arterial thrombusgPPAR- formation.  Cardiovascular Research 2005;65:907-12.

Li D, Mehta JL. Oxidized LDL, a critical factor in atherogenesis. Cardiovascular Research 2005;78:353-4.

Li D, Liu Y, Chen J, Velchala, Amani F, Nemarkommula A, Chen K, Rayaz H, Zhang D, Liu H, Sinha AK, Romeo F, Hermonat PL, Mehta JL.  Suppression of atherogenesis by delivery of TGFbeta1ACT using adeno-associated virus type 2 in LDLR knockout mice.  Biochem Biophys Res Commun 2006;344(3):701-7.

Li H, Télémaque S, Miller RE, Marsh JD.  High glucose inhibits apoptosis induced by serum deprivation in vascular smooth muscle cells via upregulation of Bcl-2 and Bc1-xl. Diabetes 54(2):540-5, 2005.

Liu Y, You H, Hermonat PL.   Studying the HPV life cycle in 3A trophoblasts and resulting pathophysiology. Methods Mol Med 2005;119:237-45.

Liu Y, Chiriva-Internati M, You C, Luo R, You H, Prasad CK, Grizzi F, Cobos E, Klimberg VS, Kay H, Mehta JL, Hermonat PL. Use and specificity of breast cancer antigen/milk protein BA46 for generating anti-self-cytotoxic T lymphocytes by recombinant adeno-associated virus-based gene loading of dendritic cells. Cancer Gene Therapy 2005; 12:304-12.   

Liu Y, Li D, Chen J,  Xie J, Bandyopadhyay S, Zhang D, Nemarkommula AR, Liu H, Mehta JL, Hermonat PL. Inhibition of atherogenesis in LDLR knockout mice by systemic delivery of adeno-associated virus type 2-hIL-10. Atherosclerosis 2006;188(1):19-27.

Liu Y, Zhou W, You C, Zheng H, You H, Liu H, Zhang D, Luo R, Kay HH, Hermonat PL. An autoimmune domain-reduced HCV core gene remains effective in stimulating anti-core cytotoxic T  lymphocyte activity. Vaccine 2006; 6;24:1615-24.

Lopez-Jimenez F, Malinski M, Gutt M, Sierra-Johnson J, Aude YW, Rimawi A, Mego P, Thomas R, Allison T, Kirby B, Hughes-Borst B, Somers V. Recognition, diagnosis and management of obesity after myocardial infarction. International Journal of Obesity 2004; 29:1-5.

Mahadevan M, Liu Y, You C, Luo R, You H, Mehta JL, Hermonat, PL. Generation of robust cytotoxic T lymphocytes against prostate specific antigen by transduction of dendritic cells using protein and recombinant adeno-associated virus.  Cancer Immunol Immunother 2007; 56(10): 1615-24.

Mango R, Biocca S, del Vecchio F, Clementi F, Sangiuolo F, Amati F, Filareto A, Grelli S, Spitalieri P, Filesi I, Favalli C, Lauro R, Mehta JL Romeo F, Novell G. A new splicing isoform of OLR1 gene is protective against acute myocardial infarction. Circulation Research 2005; 97:152-8.

Mango R, Vecchione L, Raso B, Borgiani P, Brunetti E, Mehta JL, Lauro R, Romeo F, Novelli G. Pharmacogenomics in cardiovascular disease: the role of single nucleotide polymorphisms in improving drug therapy. Expert Opinion in Pharmacotherapy 2005;6:2565-76.

Marsh JD. Progress in stroke prevention and treatment. Cardiology Rounds: Brigham and Women’s Hospital 2006; 10 (2).

Marsh JD, and (by invitation: Telemaque S, Rhee SW, Stimers JR, Rusch NJ). Delivery of ion channel genes to treat cardiovascular diseases. Transactions of the American Clinical and Climatological Association 2008; 119:171-183).

Martuscelli E, Romagnoli A, D'Eliseo A, Tomassini M, Razzini C, Sperandio M, Simonetti G, Romeo F, Mehta JL. Evaluation of venous and arterial conduits patency by 16-slice spiral computed tomography. Circulation 2004;110:3234-8

Martuscelli E, Romagnoli A, Sardella G, Tomassini M, D’Eiseo A, Chiricolo G, Razzini C, Sperandino M, Simonetti G, Mehta JL, Romeo F.  Thrombolysis in ST-segment elevation myocardial infarction: potential role of thin-slice computed tomography in the assessment of reperfusion and plaque characterization. Clin Cardiol 2006;29(7):322.

Marwali MR, Mehta JL.  COX-2 inhibitors and cardiovascular risk. Inferences based on biology and clinical studies.  J Thromb Haemost 2006;96(4):401-6.

Marwali R, Mohandas B, Hu CP, Chen J, Kavdia M, Cawich I, Johns A, Knappertz V, Deonikar P, Sawamura T, Mehta JL.   Reduction of platelet LOX-1 expression by aspirin and pravastatin; mechanism relating to nitric oxide, oxidative stress and chemokine RANTES.  American Heart Association Scientific Sessions 2006 Annual Meeting, November 12-15, Chicago, IL. Circ 2006; 54: II-71a.

Marwali MR, Hu C, Mohandas B, Dandapat A, Deonikar P, Chen J, Cawich I, Tatsuya T, Kavdia M, Mehta JL. Modulation of ADP-induced platelet activation by aspirin and pravastatin. The Journal of Pharmacol and Exp Ther 2007; 322(3).

McEwen JE, Zimniak P, Mehta JL, Shmookler-Reis RJ. Molecular pathology of aging and its implications for senescent coronary atherosclerosis. Current Opinion in Cardiology 2005; 20:399-406.

McFalls EO, Ward HB, Moritz TE, et al (Aude YW, listed in Appendix) Coronary artery revascularization prophylaxis (CARP). N Engl J Med 2004; 351:2795-804.

Mehta JL, Chen J, Yu F, Li D. Aspirin inhibits ox-LDL-mediated LOX-1 expression and metalloproteinase-1 in human coronary endothelial cells. Cardiovascular Research 2004; 64:243-9.

Mehta JL, Hermonat PL, Li D, Garza L, Novelli G. Identification and regulation of LOX-1, a receptor for Ox-LDL: Implications in atherogenesis and myocardial ischemia. In: Pharmacotherapy of Heart Failure, Eds S.K. Gupta, Pawan K., Singal, and S.S. Agrawal. New Delhi, India: Anamaya Publishers, 2005.

Mehta JL. The role of LOX-1, a novel receptor for ox-LDL, in atherosclerosis. Canadian Journal of Cardiology 2004; 20:32B-6B.

Mehta JL. Another round of prevention. Current Opinion in Cardiology 2004; 19:472.

Mehta JL, Liu Y, Chen J, Xie J, Bandyopadhyay S, Nemarkommula A, Mehta P, Li D, Hermonat PL. Successful gene therapy against atherosclerosis by rAAV  delivery of IL-10, Proceedings of the 12th World Congress on Heart Disease, Vancouver, BC, July 16-19, 2005.

Mehta JL, Chen J, Hermonat PL, Romeo F, Novelli G. Lectin-like oxidized-low density lipoprotein receptor-1 (LOX-1): A critical player in the development of atherosclerosis and related disorders.  Cardiovascular Research 2006;69:36-45.

Mehta JL, Rasouli N, Sinha A, Molavi B. Oxidative stress in diabetes: Basis of its adverse cardiac effects. The International Journal of Biochemistry & Cell Biology 2006;38:794-803.

Mehta JL, Li D, Liu Y, Hermonat PL. Suppression of atherogenesis by delivery of TGFβ1ACT using adeno-associated virus type 2 in LDL knockout mice. http://www.athero.org/commentaries/comm532.pdf  2006.

Mehta JL, Bursac Z, Hauer-Jensen M, Fort C, Fink LM. Comparison of mortality rates in statin users versus nonstatin users in a United States veteran population.  A J Cardiol 2006; 98(7):923-8.

Mehta JL. Critical Role of Dyslipidemia and Angiotensin II in Atherogenesis. In: Molecular Mechanisms of Hypertension, Ed. Re R, Schiffrin E, Sowers J, and DiPette D. Taylor & Francis Medical Books, London, 2006. pp 375-384.

Mehta JL. Oxidized or native low-density lipoprotein cholesterol: which is more important in atherogenesis?  J Am Coll Cardiol 2006;48(5):980-2. Editorial.

Mehta JL, Attramadal H.  The TGFbeta superfamily in cardiovascular biology.  Cardiovasc Res 2007;74(2):181-3. Editorial.

Mehta JL, Sanada N, Hu CP, Chen J, Dandapat A, Sugawara F, Satoh H, Inoue K, Kawase Y, Jishage K, Suzuki H, Takeya M, Schnackenberg L,  Beger R, Hermonat PL, Sawamura T.  Deletion of LOX-1 reduces atherogenesis in LDLR knockout mice fed high cholesterol diet. Circ Res 2007; 100(11):1634-42.

Milstein ML, McFarland TP, Marsh JD, Cala SE. Inefficient glycosylation leads to high steady-state levels of actively degrading cardiac triadin – 1. Journal of Biological Chemistry 2008; 283(4):1929-35. 

Mohandas B, Singh B, Mehta JL, Sachdeva R.  A man with four coronary arteries.  Eur Heart J 2007; 28(11):1357.

Molavi B, Mehta JL. Oxidative stress in cardiovascular disease: molecular basis of its deleterious effects, its detection, and therapeutic considerations. Current Opinion in Cardiology 2004;19:488-493.

Molavi B, Mehta JL: Cardioprotective effects of Rosiglitazone against ischemia-reperfusion injury are associated with modulation of angiotensin receptor expression and signaling. Journal of the American College of Cardiology 2004; 5: 305.

Molavi B, Rasouli N, Kern PA.  The prevention and treatment of metabolic syndrome and high-risk obesity.  Curr Opin Cardiol 2006; 21(5):479-85.

Molavi B, Chen J, Mehta JL. Cardioprotective effects of rosiglitazone are associated with selective overexpression of type 2 angiotensin receptors and inhibition of p42/44 MAPK.  American Journal of Physiology: Heart Circ Physiol 2006; 291(2):H687-93.

Molavi B, Bagwe S, Mehta JL. Obesity and glucose intolerance is associated with diastolic dysfunction. Exposing the Achilles heel of early diabetic cardiomyopathy. Southern Society for Clinical Investigation meetings, New Orleans, LA, February, 2007;50:S195a.

Muscoli C, Sacco I, Alecce W, Palma E, Nistico R, Costa N, Clementi F, Rotiroti D, Romeo F, Salvemini D, Mehta JL, Mollace V. The protective effect of superoxide dismutase mimetic M40401 on balloon injury-related neointima formation: role of the lectin-like oxidized low-density lipo-protein receptor-1. Journal of Pharmacology and Experimental Therapeutics 2004; 311:44-50.

Nassief A, Marsh JD. Statin therapy for stroke prevention. Stroke 2008; 39(3): 1042-8.

Novelli G, Borgiani P, Mango R, Romeo F, Mehta JL. OLR1 gene and coronary artery disease/acute myocardial infarction: replication in an independently collected sample.  Eur J Hum Genet 2006. 14(8):894-5. Letter to Editor.

Quindry J, French J, Hamilton K, Lee Y, Mehta JL, Powers S. Exercise training provides cardioprotection against ischemia–reperfusion induced apoptosis in young and old animals. Experimental Gerontology 2005; 40:416-25.

Rajamani K, Sunbulli M, Jacobs BS, Berlow E, Marsh JD, Kronenberg M,  McLaughlin P, Vouyouka A, Levine SR, Lai Z, Chaturvedi S. Detection of carotid stenosis in African Americans with ischemic heart disease. Journal of Vascular Surgery 43(6): 1162-1165, 2006.

Ram ML, Kiarash A, Marsh JD, Cala SE. Phosphorylation and dephosphorylation of calsequestrin on CK2-sensitive sites in heart. Mol Cell Biochem 2004; 266:209-217.

Ramappa P, Thatai D, Coplin W, Gellman S, Carhuapoma JR, Quah R, Atkinson B, Marsh JD. Cardiac Troponin-I: A predictor of prognosis in subarachnoid hemorrhage. Journal of Neurocritical Care 2007; December 18 [Epub ahead of print]. 

Rasouli N, Molavi B, Elbein SC, Kern PA.  Ectopic fat accumulation and metabolic syndrome.  Diabetes Obes Metab 2007;9(1):1-10.

Ridker PM, Brown NJ, Harrison DG, Mehta JL, Vaughn DE. Established and emerging plasma biomarkers in the prediction of first atherothrombotic event. Circulation 2004: 109 (25 Suppl 1):IV6-IV19.

Robinson E, Bissett J, Smith ES. Amiodarone toxicity and surveillance. J Ark Med Soc 2005; 101:308-9.

Romeo F, Leo R, Clementi F, Razzini C, Borzi M, Martuscelli E, Pizzuto F, Chiricolo G, Mehta JL.  Multislice computed tomography in an asymptomatic high-risk population. Am J Cardiol 2007; 99(3):325-8.

Rossi NF, Black SM, Télémaque-Potts S and Chen H. Neuronal nitric oxide synthase activity in paraventricular nucleus buffers central ET-1-induced pressor response and AVP secretion. J Cardiovasc Pharmacol 2004; 44 (suppl 1): S283-8.

Sabatine MS, Cannon CP, Gibson CM, et al for the CLARITY-TIMI 28 investigators Aude YW, listed in Appendix). Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation. N Engl J Med 2005;352:1179-89.

Sarkar K, Mehta JL. Apoptosis in atherosclerosis: Virtue or ViceCurrent Cardiology Review 2005,1:141-152.

Sarkar K, Sinha A, Mehta JL. The role of statins in endothelial dysfunction in hypertension. Current Opinion in Cardiology. 2006;21:316-21.

Sarkar K, Sharma SK, Sachdeva R, Romeo F, Garza L, Mehta JL.  Coronary artery restenosis: vascular biology and emerging therapeutic strategies.  Expert Rev Cardiovasc Ther 2006; 4(4):543-56.

Sarkar K, Sinha AK, Mehta JL.  The role of statins in endothelial dysfunction in hypertension. Curr Opin Cardiol 2006; 21(4):316-21.

Sachdeva R, Sarkar K, Sureddi RK. Myocardial ischemia due to kinking of left internal mammary artery graft with the expiratory phase of respiration.  J Invasive Cardiol 2007; 19(5):241-2.

Saucedo JF, Garza L, Wolford DC, Cook SL, Ramanathan KB, Matin Z, McGrew FA, Jacoski MV, Jennings LK. Tennessee-Arkansas-Mississippi (TAM) Clinical Research Consortium. Comparative pharmacodynamic evaluation of eptifibatide and tirofiban HCl in patients undergoing percutaneous coronary intervention (the TAM1 Study). [Clinical Trial. Journal Article. Multicenter Study. Randomized Controlled Trial] American Journal of Cardiology 2004; 93:1279-82.

Saucedo JF, Lui HK, Garza L, Guerra J, Jacoski MV, Jennings LK. Comparative pharmacodynamic evaluation of Eptifibitide and Abciximab in patients with Non_ST segment elevation acute coronary syndromes. The TAM 2 Study. Journal of Thrombosis and Thrombolysis 2004; 18: 67-74.

Saucedo JF, Aude YW, Garza L. Pharmacodynamic evaluation of Bivalirrubin and Clopidogrel with or without Integrilin: Results of a randomized study. Am J Cardiol 2005;95:1453-6.

Saucedo JF, Aude YW, Pacheco R, Thorn B, Matin Z, Husain K, Garza L. Inhibition of platelet aggregation with Eptifibatide, Bivalirudin, and Heparin in patients undergoing Percutaneous Coronary Intervention receiving Clopidogrel pre-Treatment. (The Pharmaco-Dynamic Evaluation of Angiomax, Clopidogrel With Or Without INtegrilin [DEACON] Study). American Journal of Cardiology 2005; 95:1453-1456.

Schror K, Mehta P, Mehta JL. Cardiovascular risk of selective COX-2 inhibitors (Editorial). Journal of Cardiovascular Pharmacology and Therapeutics 2005;10:95-101.

Sepulveda JL, Mehta JL. C-reactive protein and cardiovascular disease: a critical appraisal. Current Opinion in Cardiology 2005; 20:407-16.

Shen YH, Utama B, Wang J, Gan Y, Wang X, Wang J, Vercellotti GM, LeMaire SA, Coselli JS, Mehta JL, Wang XL. Human cytomegalovirus inhibits Akt-mediated eNOS activation through upregulating PTEN (phosphatase and tensin homolog deleted on chromosome 10). Cardiovascular Research 2006;69:502-11.

Sinha AK, Mehta JL. Modulation of atherosclerosis, blood pressure and arterial elasticity by statins.  In: Atherosclerosis, Large Arteries and Cardiovascular Risk, edited by ME Safar and ED Frohlich, A Volume in the series Advances in Cardiology. S. Karger AG, Basel, Switzerland. 2006.

Sinha AK, Mehta JL.  Modulation of atherosclerosis, blood pressure and arterial elasticity by statins.  Advanced Cardiology 2007;44:315-30.

Sonkusare S, Fraer M, Marsh JD, Rusch NJ.  Disrupting calcium channel expression to lower blood pressure: new targeting of a well-known channel.  Mol Interv 2006; 6(6)304-10.

Sonkusare S, Palade PT, Marsh JD, Télémaque S, Pesic A and Rusch NJ.  Vascular calcium channels and high blood pressure: pathophysiology and therapeutic implications. Vasc Pharmacol 2006;44:131-42.

Sonkusare S, Stimers JR, Grain T, Marsh JD, Télémaque S.  Expression of beta2 subunit mutants alters calcium currents in HL-1 cells.  FASEB J 2006; 2 (5, Part II): A1114.

Sukhija R, Aronow WS, Kakar P, Garza L, Sachdeva R, Sinha A, Mehta JL.  Relation of microalbuminuria and coronary artery disease in patients with and without diabetes mellitus. Am J Cardiol  2006; Aug 1;98(3):279-81.

Sukhija R, Kakar P, Mehta V, Mehta JL.  Enhanced 11beta-hydroxysteroid dehydrogenase activity, the metabolic syndrome, and systemic hypertension.  Am J Cardiol 2006; Aug 15;98(4):544-8.

Sukhija R, Bursac Z, Mohandas B, Sachdeva R, Garza L, Aude W, Sinha A, Mehta JL. Effect of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors (statins) on renal function.  American Heart Association Scientific Sessions 2006 Annual Meeting, November 12-15, Chicago, IL. Circ. 2006; 114:II-906a.

Sukhija R, Eigenbrodt M, Rose K, Coupe D, Brancati F, Mehta JL. common carotid artery diameter is a predictor of myocardial infarction in middle-aged women. American Heart Association Scientific Sessions 2006 Annual Meeting, November 12-15, Chicago, IL. Circ. 2006; 114: II-825a.

Sukhija R, Aronow W, Kakar P, Sachdeva R, Garza L, Sinha A, Mehta JL. Microalbuminuria is Associated With Severe Angiographic Coronary Artery Disease in Diabetics and Non-Diabetics. Journal of  the American College of Cardiology 2006;47:358A.

Sukhija R, Bursac Z, Mehta JL. Effect of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors on fasting blood sugar. Southern Society for Clinical Investigation meetings, New Orleans, LA, February, 2007;50:S211a.

Sukhija R, Fahdi I, Garza L, Fink L, Scott M, Aude W, Pacheco R, Bursac Z, Grant A, Mehta JL.  Inflammatory markers, angiographic severity of coronary artery disease, and patient outcome.  Am J Cardiol  2007; Apr 1;99(7):879-84.

Sukhija R, Mehta V, Leonardi M, Mehta JL.  Implantable cardioverter defibrillators for prevention of sudden cardiac death.  Clin Cardiol 2007; 30(1):3-8.

Sukhija R, Bursac Z, Mehta JL. Effect of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors on fasting blood sugar. Southern Society for Clinical Investigation meetings, New Orleans, LA, February, 2007;50:S211a.

Sullivan DH, Roberson PK, Smith ES, Price JA, Bopp MM.  Effects of muscle strength training and megestrol acetate on strength, muscle mass, and function in frail older people.  J Am Geriatr Soc 2007; 55(1):20-8.

Telemaque S. and Wang Z. Identification of target proteins for neuronal calcium sensor-1 (NCS-1) in the heart. Circulation 2006; 114(18):II-93.

Telemaque S, Liu DS, Grain T, Liu M-Y, Liu SJ. Overexpression of neuronal calcium sensor-1 alters contractile function in adult rat ventricular myocytes. FASEB J 2006; 20(5, Part II): A1446.

Telemaque S, Mehta JL.  Sepsis, calcineurin, and cardiac dysfunction: the saga of life and death.  J Am Coll Cardiol 2007; Jan 30;49(4):500-1. Editorial.

Telemaque S, Sonkusare S, Grain T, Rhee SW, Stimers JR, Rusch NJ, Marsh JD. Design of mutant  b2 subunits as decoy molecules to reduce the expression of functional Ca2+  channels in cardiac cells. Journal of Pharmacology and Experimental Therapeutics 2008; 325 (1)37-46. 

Trigwell S, De S, Sharma R, Mazumder MK, and Mehta JL. Structural evaluation of radially expandable cardiovascular stents encased in a polyurethane film. Journal of Biomedical Materials Research B Applied Biomaterials 2006; 76(2):241-50.

Viswamitra S, Higgins CB, Meacham DF, Mehta JL. Magnetic resonance imaging in myocardial ischemia. Current Opinion in Cardiology 2004; 19:510-516.

Wang H, Mehta JL, Chen K, Zhang X, Li DY. Human urotensin II modulates collagen synthesis and the expression of MMP-1 in human endothelial cells. Journal of Cardiovascular Pharmacology 2004; 44:577-81.

You H, Liu Y, Prasad CP, Agrawal N, Zhang D, Bandyopadhyay S, Liu H, Kay HH, Mehta JL, Hermonat PL. Multiple human papillomavirus genes affect the adeno-associated virus life cycle.Virology 2005; 344(2):532-40.

You H, LiuY, Cong M, Ping W, You C, Zhang D, Mehta JL, Hermonat PL.  HBV genes induce cytotoxic T-lymphocyte response upon adeno-associated virus (AAV) vector delivery into dendritic cells.  J Viral Hepat 2006; 13(9):605-12.

You H, Liu, Y, Cong M, You CX, Mehta JL, Hermonat, PL. HBV genes induce cytotoxic T lymphocyte response upon adeno-associated virus (AAV) vector delivery into dendritic cells, Journal of Viral Hepatitis 2006; 13(9): 605-12.

Zhang W, Li D, Mehta JL. Role of AIF in human coronary artery endothelial cell apoptosis. American Journal of Physiology 2004; 286:H354-8.

 

 

Contact regarding webpage content: GibAnn Berryhill

 

University of Arkansas for Medical Sciences
College of Medicine

Department of Internal Medicine, Slot 832

4301 W. Markham
Little Rock, AR 72205