The research fields are as follows:
1. Studies on the structure/function relationship and expression of genes related to human diseases or important biological function. By using molecular biology techniques, cell differentiation and growth in neural and reproductive systems and in certain diseases have been studied. By decoding the human genome to explore some hitherto unknown disease-related genes and their characteristics, the nature of disease at the molecular level may be illuminated, thus providing a theoretical basis and guidelines f or treat, and eventually leading to effective biological products for diagnostic, preventive or clinical use.
2. Studies on the control mechanisms of gene expression and signal transduction involved in cellular functions and the pathogenesis of disease. Research projects are focused on the regulation of cell-type, specific expression of some important genes, wit h special emphasis on transcriptional regulation and the expression of foreign genes or the functional regulatory elements of the genes in transgenic animals. Research is also underway to explore the mechanisms and signal transduction pathways leading to the "on-off" switching of some important genes. Achievements in these studies may be helpful in defining the nature of cell-type specificity, growth, differentiation, and the programmed death of the cells. The techniques to "knock-out" of certain genes ma y also be very useful in providing transgenic animal models for future gene therapy.