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Kelly Mercer, BS, PhD
Instructor

UAMS Campus, COPH Bldg.
3rd Floor, Rm 306-2
(501) 526-7876
(Fax) (501) 526-5934
kmercer@uams.ed

Department: Environmental and Occupational Health

 

 

Education:

9/01  —  9/03      Postdoctoral Fellowship, Department of Pharmaceutical                          Sciences, St. Jude Children’s Research Hospital, Memphis, TN 

8/97  —  8/01      PhD, Department of Biochemistry and Molecular Biology, University of  Arkansas for Medical Sciences, Little Rock, AR.

8/93  —  5/97      BS, University of Dallas, Irving, TX.

Research Interests:

My research interests include a project that was started during my postdoc in Dr. Susan Kadlubar’s laboratory.  Most of the chemotherapeutic strategies for treating breast cancer involve generating reactive oxygen species (ROS) to kill the tumor cells by initiating apoptosis.  Cellular ROS is regulated by antioxidant mechanisms.  In cancer, some antioxidant enzymes are elevated to protect the tumor cell from the highly oxidative environment necessary to promote tumor growth.  I am interested to see the relationship between these antioxidant pathways and response to chemotherapy, and if genetic variation within key enzymes of these pathways play a role in that response.

 





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