Dr. Daohong Zhou is Professor of Pharmaceutical Sciences at University of Arkansas for Medical Sciences (UAMS).
Dr. Daohong Zhou’s research focuses on radiation and chemotherapy induced hematopoietic stem cell injury and leukemia and on development of mechanism-based strategies to protect the hematopoietic system from cancer therapy-induced damage and novel medical countermeasures against radiological/nuclear accidents or terrorism.
Dr. Daohong Zhou has published more than 50 peer reviewed scientific articles and book chapters. His research is well funded by grants from the National Cancer Institute (NCI) and National Institute of Allergy and Infectious Disease (NIAID).
Dr. Daohong Zhou serves on several national and international peer review panels. He is a regular member of the Radiation Therapeutics and Biology Study Section, the panel that reviews radiation-related projects submitted to the National Institutes of Health (NIH).
Dr. Daohong Zhou has been named as the Winthrop P. Rockefeller Endowed Chair for Leukemia Research at the Winthrop P. Rockefeller Cancer Institute. He is also an Honorary Professor of the Peking Union Medical College in China.
Recent Publications
1.
Wang Y, Liu L, Pazhanisamy SK, Li H, Meng A, Zhou D (2009). Total body irradiation causes residual bone marrow injury in part by selective induction of persistent oxidative stress in murine hematopoietic stem cells. Free Radical Biology and Medicine, 48: 348-356. PMID: 19925862
2.
Johnson SM, Torrice C, Bell JF, Monahan KB, Jiang Q, Wang Y, Ramsey MR, Jin J, Wong K, Su L, Zhou D, Sharpless NE (2010). Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition. J Clin Invest, 120: 2527-2536. PMID: 20577054
3.
Wu L, Shao L, An N, Wang J, Pazhanisamy S, Feng W, Hauer‑Jensen M, Miyamoto S, Zhou D (2011). IKKβ regulates the repair of DNA double-strand breaks induced by ionizing radiation in MCF-7 breast cancer cells. PLoS One, 6(4):e18447. PMID: 21490922
4.
Pazhanisamy SK, Li H, Wang Y, Batinic-Haberle I, Zhou D (2011). NADPH oxidase inhibition attenuates total body irradiation-induced hematopoietic genomic instability. Mutagenesis,26(3): 431-435.
5.
Wang Y, Kellner J, Liu L, Zhou D (2011). Inhibition of p38 mitogen-activated protein kinase promotes ex vivo hematopoietic stem cell expansion. Stem Cell & Dev, ahead of print. doi:10.1089/scd.2010.0413. PMID: 21415439
6.
Wang Y, Scheiber MN, Neumann C, Calin GA, Zhou D (2011). MicroRNA Regulation of Ionizing Radiation-Induced Premature Senescence. Int J Radiat Oncol Biol Phys, ahead of print. doi:10.1016/j.ijrobp. 2010.09.048. PMID: 21093163
7.
Li H, Wang Y, Pazhanisamy SK, Shao L, Batinic-Haberle I, Meng A, Zhou D (2011). Mn (III) meso-tetrakis (N-ethylpyridinium-2-yl) porphyrin mitigates total body irradiation-induced long-term bone marrow suppression. Free Radical Biology and Medicine, ahead of print. doi:10.1016/j.freeradbiomed. 2011.04.016. PMID: 21565268
ahead of print. doi:10.1016/j.ijrobp. 2010.09.048.