Division of Radiation Health
Faculty Member
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Snehalata Pawar, PhD.
Assistant Professor of Pharmaceutical Sciences
Member, Division of Radiation Health
E-mail address: SApawar@uams.edu
Phone: 501-686-5784 (office)
Fax: 501-686-6057
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- Dr. Pawar received her Ph.D. in Biochemistry from the National ChemicaL Laboratory (affiliated to University of Pune), Pune. She received postdoctoral training at the M.D. Anderson Cancer Center, Houston, TX and at the National Cancer Institute, Frederick, MD.
- Dr. Pawar is Instructor of Pharmaceutical Sciences at University of Arkansas for Medical Sciences (UAMS), member of the College of Pharmacy Division of Radiation Health.
- Dr. Pawar's research focuses on the role of the CCAAT enhancer binding protein (C/EBP) family of transcription factors in radiation-induced enteropathy and understanding the molecular mechanisms via which C/EBPs participate in the DNA damage response using the endothelial, intestinal and mammary epithelial cell systems. The overall goal of this research is to develop novel therapeutic interventions for improved cancer survivorship as well as development of radiation countermeasure agents.
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Recent Publications |
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Pawar S.A., Roy-Sarkar, T., Kuppuswamy, B., Wang, J., Zhang Y., Dowdy S., Huang, A., Sharan S, and Sterneck, E. C/EBPδ targets cyclin D1 for proteasome-mediated degradation via induction of CDC27/APC3 expression. Proc. Natl. Acad. Sci. USA. 107:9210-5, 2010. PMID: 20439707 |
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Chen, N., Szentirmay, M.N., Pawar, S.A., Sirito, M., Wang, J., Wang, Z., Zhai, Q., Yang, H-X., Peehl, D.M., Ware, J.L. and Sawadogo, M. Tumor-suppression functions of transcription factor USF2 in prostate carcinogenesis. Oncogene, 25, 579-87, 2006. PMID: 16186802 |
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Pawar, S. A., Szentirmay, M., Hermeking, H. and Sawadogo, M. Evidence for a gene-specific switch at the CDK4 promoter with loss of control by both USF and c-Myc. Oncogene, 23, 6125-6135, 2004. PMID: 15208653 |
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Szentirmay, M.N., Yang, X-H., Pawar, S.A., Vinson C. and Sawadogo, M. The IGF2 receptor (IGF2R) is a USF2-specific target in mammary epithelial cells, but not in breast cancer cells. J. Biol. Chem. 278, 37231-37240, 2003. PMID: 12857727 |
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