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Dr. Aykin-Burns received her Ph.D. degree from the University of Missouri-Rolla (currently known as Missouri University of Science and Technology) focusing on antioxidant-based therapies in lead poisoning. She received postdoctoral training at the Free Radical and Radiation Biology Program (FRRBP), Department of Radiation Oncology at the University of Iowa.
Dr. Aykin-Burns is Assistant Professor of Pharmaceutical Sciences at University of Arkansas for Medical Sciences (UAMS), member of the College of Pharmacy Division of Radiation Health.
Dr. Aykin-Burns's research focuses on reactive oxygen species (ROS), radiation induced (IR and UV) normal tissue damage and wound healing as well as polychlorinated biphenyl (PCB) induced oxidative stress.
Recent Publications
1. Aykin-Burns, N., Slane, B.G., Liu, A.T.Y., Owens, K.M., O’Malley, M.S., Smith, B.J., Domann, F.E., Spitz, D.R. (2011) Sensitivity to low dose/low LET ionizing radiation in mammalian cells harboring mutations in succinate dehydrogenase subunit C is governed by mitochondrial derived reactive oxygen species. Radiat Res 175, 150-158. PMID:21268708
2. Ross C., Alston, M., Bickenbach, J.R., Aykin-Burns, N. (2011) Oxygen tension changes the rate of migration of human skin keratinocytes in an age-related manner. Exp Dermatol 20:58-63. PMID:21158939
3. Kim, H.S., Patel, K., Muldoon-Jacobs, K., Bisht, K.S., Aykin-Burns, N., Pennington, J.D., van der Meer, R., Nguyen, P., Savage, J., Owens, K.M., Vassilopoulos, A., Ozden, O., Park, S.H., Singh, K.K., Abdulkadir, S.A., Spitz, D.R., Deng, C.X., Gius, D. (2010) SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress. Cancer Cell 17, 41-52. PMID:20129246
4. Zhu, Y., Kalen, A.L., Li, L., Lehmler, H.J., Robertson, L.W., Goswami, P.C., Spitz, D.R., Aykin-Burns, N. (2009) Polychlorinated-biphenyl-induced oxidative stress and cytotoxicity can be mitigated by antioxidants after exposure. Free Radic Biol Med 47, 1762-1771. PMID:19796678
5. Aykin-Burns, N., Ahmad, I. M., Zhu, Y., Oberley, L. and Spitz, D. R. (2009) Increased levels of superoxide and hydrogen peroxide mediate the differential susceptibility of cancer cells vs. normal cells to glucose deprivation. Biochem J 418, 29-37. PMID:18937644
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