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Dr. Allaben is Associate Professor of Pharmaceutical Sciences at University of Arkansas for Medical Sciences and Program Manager for Biomedical Advanced Research and Development Authority (BARDA) contract supporting the develop a therapeutic intervention for Acute Radiation Syndrome.
Dr. Allaben is a Fellow of the Academy of Toxicological Sciences (ATS), a Board Certified Toxicologist and an Officer and Board member of the Toxicology Forum, Inc.
Dr. Allaben retired from the U. S. Food and Drug Administration in 2009 after 33 years of public service where he was Associate Director for Scientific Coordination, FDA’s Director guiding the Agency’s participation in the National Toxicology Program (NTP) and Project Officer for a FDA-National Institutes of Environmental Health Sciences (NIEHS) Interagency Agreement with management and fiscal responsibility for a multi-million dollar/multi-task research and testing program
Dr. Allaben’s research focused on mechanisms of toxicity and carcinogenicity as modulated by dietary control through diet constituent manipulation and/or dietary restriction; he has published over 100 research articles, book chapters and technical reports.
Dr. Allaben has received Department of Health and Human Services (DHHS) Career Achievement Award, FDA’s Distinguished Career Achievement Award, FDA’s Award of Merit, NTP’s 25 Year Dedicated Service Award and the Toxicology Forum’s Dedicated Service Award.
Recent Publications
1. William T. Allaben, Angelo Turturro, Julian E. A. Leakey, John E. Seng and Ronald W. Hart; FDA’s Points-to-Consider Document: The Need for Dietary Control for the Reduction of Experimental Variability within Animal Assays and The Use of Dietary Restriction to Achieve Dietary Control. Toxicologic Pathology, 24:776 - 781, 1996. PMID: 8994309
2. Angelo Turturro, Bruce Hass, Ronald Hart, and William T. Allaben, Body Weight Impact on Spontaneous Diseases in Chronic Bioassays, International Journal of Toxicology, Volume 17 (Supplement 2): 79-99, 1998. (IJT.SAGEPUB)
3. J. E. A. Leakey, J. E. Seng, N. Hassain, L. J. Allen and W. T. Allaben, Dietary Controlled Carcinogenicity Study of Chloral Hydrate in Male B6C3F1 Mice, Toxicol. Appl. Pharmacol.,193: 266 - 280, 2003. PMID: 14644627
4. Julian E. A. Leakey, John E. Seng and William T. Allaben, Influence of Body Weight, Diet, and Stress on Aging, Survival and Pathological Endpoints in Rodents: Implications for Toxicity Testing and Risk Assessment, Regulatory Research Perspectives, 4(2):1-29, 2004. (RRP: UCM061854)
5. Ajay Joseph, Taewon Lee, Carrie L. Moland, William S. Branham, James C. Fuscoe, Julian E.A. Leakey, William T. Allaben, Sherry M. Lewis, Akhtar A. Ali, Varsha G. Desai, Effect of (+)-Usnic Acid on Mitochondrial Functions as Measured by Mitochondria-specific Oligonucleotide microarray in Liver of B6C3F1 Mice, Mitochondrion 9 (2009) 149–158. PMID: 19460291
6. Akhtar, A. Ali, Sherry M. Lewis, Heidi L. Badgley, William T. Allaben, Julian E. A. Leakey, Oral Glucosamine Increases Expression of Transforming Growth Factor β1 (TGFβ1) and Connective Tissue Growth Factor (CTGF) mRNA in Rat Cartilage and Kidney: Implications for Human Efficacy and Toxicity, Arch Biochem Biophys. 2011 Jun 1; 510(1):11-18. PMID: 21466783 |
