Degrees

B. S. (Pharmacy), University of Wisconsin

Ph. D. (Pharmaceutical Chemistry-Medicinal Chemistry), University of Kansas

Teaching Specialty

Medicinal Chemistry

Research Interests

Synthesis of and Biochemical and Pharmacological Activities of Essential Metalloelement Complexes for Use in Prevention and/or Treatment of Chronic Degenerative Diseases Including: Arthritis, Gastrointestinal Ulcers, Epilepsy, Cancers, Diabetes, Atherosclerosis, Cardiovascular Disease, Non-Lethal and Lethal Radiation Injury, Stroke, and Myocardial Infarction.

Service Activities

Director of the Essential Metallolement Analysis Laboratory

Consulting

Professional Honors

• Selected as one of 2000 OUTSTANDING SCHOLARS OF THE 20TH CENTURY by The International Biographical Centre, Cambridge, England.
• Selected as one of 2000 INTELLECTUALS OF THE 20TH CENTURY by The International Biographical Centre, Cambridge, England.
• Selected as one of 2000 OUTSTANDING PEOPLE OF THE 20TH CENTURY by The International Biographical Centre, Cambridge, England.
• Selected as INTERNATIONAL MAN OF THE YEAR by The International Biographical Centre, Cambridge, England.
• Selected as MAN OF THE YEAR FOR 2000 by the American Biographical Institute.
• Nominated as Fellow of the Nutrition Research Academy by Professor R. K. Chandra, Janeway Child Health Centre, Saint John’s Newfoundland, Canada.

Recent Publications

1. Donham,D.C. and Sorenson, J.R.J.: Calcium(II)3(3,5-diisopropylsalicylate)6(H2O)6 Activites Nitric Oxide Synthase: An Accounting for Its Action in Decreasing Platelet Aggregation. Metal-Based Drugs (7: 77-88, 2000).
2. Morgant,G., Dung, N.-H., Daran, J.-C., Voissat, B., Labouze, X., Roch-Arveiller, M.l Greenaway, F. T. Cordes, W., and Sorenson, J.R.J.: Low-Temperature Crystal Structures of Tetrakis-?-3,5-diisopropylsalicylatobis-dimethyformamidodicopper(II) and Tetrakis-?-3,5-diisopropylsalicylatobis-diethyletheratodicopper(II) and Their Role in Modulation Polymorphonuclear Leukocyte Activity in Overcoming Seizures. J. Inorg. Biochem. (81: 11-22, 2000).
3. Sorenson, J.R.J., Soderberg, L.S.F., Chang, L.W. and Walker, R.B.: Repair of Radiation Injury with Essential Metalloelement Chelates. Proced. Soc. Exptl. Biol. Med. (In Revision) (Invited).
4. Sorenson, J.R.J.: A Review of: Metal Ions in Biological Systems. Volume 37. Manganese and Its Role in Biological Processes Ed. By A. Sigel and H. Sigel, Marcel Dekker, New York, N.Y. J. Med. Chem. 43: 2969, 2000).
5. Homoncik, M., Jilma, B., Donham, D. C., Frossard, M., Kreuzer, C, and Sorenson, J.R.J. Activation of Calcium-Dependent Calmodulin by Ca(II)3(3,5-DIPS)6 Decreases Thrombin-Induced P-Selectin Expression.(In Press)

E-mail Address: SorensonJohnR@exchange.uams.edu