Degrees

B.S.; Tennessee Technological University
B.S., Ph.D.; University of Tennessee

Teaching Specialty

• Clinical Pharmacokinetics - Pharm 4464
• Medical and Pharmaceutical Applications - PHSC 5464
• Special Problems in Pharmaceutical Sciences - PHSC 5262
• Pharmaceutical Analysis - Biopharm 3273
• Computer Applications in Pharmacokinetics and Biopharmaceutics

Research Interests

My research interests are currently focused on in estimating:

• The potential for herbal dietary supplements to modulate CYP450 enzyme systems and thus interact with conventional medications;
• The effects of aging and inflammation on p-glycoprotein mediated drug transport across the blood-brain barrier;
• Kupffer cell activation and its role in modulating hepatic CYP450 activity; and
• Investigation of the pharmacology and toxicity of ephedra-containing dietary supplements.

Campus Service Activities

UAMS, College of Pharmacy

• Undergraduate Admissions Committee (1994 - present)
   
• Student/Faculty Affairs Committee (1991- present)
• Scholastic Standing Committee (1995 - present)
   
• Graduate Committee (1995-present)
   
• Promotion and Tenure Committee (1995-present)
   
• Executive Committee (1996-present)
   
• Joint Pharm. D./Ph.D. Study Committee (1996-present)
   
• Pharmaceutical Sciences Seminar Course Committee (1996-present)
   
• Chairman (interim), Department of Pharmaceutics (9/1/1996-12/1/1998)

University of Arkansas for Medical Sciences

• Academic Senate Library Advisory Committee (1989 - present)
   
• Institutional Animal Care and Use Committee (1992 - present)
   
• Tenure Task Force Committee (1997 - present)
   
• Copyright Review Committee (1998 - present)
   

Professional Honors

• 2000 - UAMS Department of Pharmaceutical Sciences "Most Outstanding Faculty" Award
• 1997, 1995 - LLoyd R. Thompson Memorial Award for the "Most Outstanding Professor in the UAMS Department of Pharmaceutics"
• 1994 - R. Clifton Brooks Medical Research Fellowship
• 1987 - University of Tennessee, Memphis, Sigma Xi Research Recognition Award (First Place)
• Outstanding Young Men in America, 1988

Recent Publications

1. Barone GW, Gurley BJ, Ketel BL, Lightfoot ML, Abul-Ezz SR. Drug interaction between St. John?s Wort and cylosporine. Annals of Pharmacotherapy 34:1013-1016, 2000.
2. Abul-Ezz S, Barone GW, Gurley BJ, et al. St John's Wort Linked to Kidney Rejection. Nephrology News & Issues 66:2000.
3. Barone GW, Gurley BJ, Ketel BL, and King KE. The tolerability of newer immunosuppressives in a patient with acute intermittent porphyria. Journal of Clinical Pharmacology 41:113-115, 2001.
4. Barone GW, Gurley BJ, Ketel BL, Lightfoot ML, and Abul-Ezz. Comment: drug-herb interaction. Annals of Pharmacotherapy 35:124-125, 2001.
5. Barone GW, Gurley BJ, Ketel BL, and Abul-Ezz SR. Herbal dietary supplements: a source for drug interactions in transplant recipients. Transplantation 71:239-241, 2001.
6. Kommuru TR, Gurley B, Khan MA, and Reddy IK. Self-emulsifying drug delivery systems (SEDDS) of coenzyme Q10: formulation development and bioavailability assessment. International Journal of Pharmaceutical Sciences 212:233-246, 2001.
    

Recent Media Quotes and Appearances

• Appearance on CNN, (national television broadcast ). August 4, 1999 regarding Ephedra dietary supplements.
   
• Quoted and study cited in Washington Post, March 25, 2000, "Natural Medicines."
   
• Appearance on Dateline NBC (national television broadcast). April 18, 2000, "How safe is ephedra?"
   
• Appearance on Fox News Channel (national television broadcast). April 20, 2000 regarding quality control of herbal dietary supplements.
   
• Quoted on LA Times website (www.latimes.com). April 24, 2000. "Some types of ephedra can be dangerous"
   
• Study cited in U.S. News & World Report. May 5, 2000. "Herbs and prescriptions can make a risky mixture"
   
• Quoted in Washington Post. May 2, 2000. "Findings of fact: A reality check on product claims"
   
• Study cited in New York Times. May 2, 2000. "Standards; when the label doesn't measure up."
   
• Quoted and study cited on CBS News Healthwatch website (www.cbsnews.com). "Herb/drug interactions: sometimes dangerous." May 2000.
   
• Quoted and study cited in San Francisco Chronicle. June 2, 2000. "Herb Remedies: Panacea or Problem?"
   
• Quoted and study cited on CBS News Healthwatch website (www.cbsnews.com). "Herbal fraud: let the buyer beware." June 2000.
   
• Study cited in Washington Post.June 18, 2000 "Diet Supplement Marketers Target Kids."
   
• Appearance on MSNBC Homepage (national television broadcast). June 29, 2000, regarding adverse effects of Ephedra-containing dietary supplements.
   
• Appearance on KHTV Channel 11 (statewide broadcast in Arkansas). September 27, 2000.
   
• Appearance on CNN, (national television broadcast ). November 6, 2000 regarding Ephedra dietary supplements.
   
• Quoted in The Philadelphia Inquirer, November 13, 2000, “What’s behind latest drug warnings.
   
• Quoted and study cited in cover story for U.S. News & World Report , “The Risks of Natural Cures, February 12, 2001.
   

E-mail Address: GurleyBillyJ@uams.edu