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Departments and Programs Faculty Philip Breen, B.S. (Pharmacy), Ph.D.
Degrees
Teaching Specialty
Research Interests Pharmacokinetics and Pharmacodynamics of Inhaled Drugs; Pharmacokinetics and Pharmacodynamics in Microgravity; Food Safety. The objective of my pharmacokinetic research is to determine the mathematical relationship between a drug's dose and its plasma concentration; while my pharmacokinetic / pharmacodynamic research aims at the determination mathematical models that will predict pharmacological effect directly from dose regimen data. My food safety research involves the application of antimicrobial agents to greatly inhibit the growth of viable food pathogens and to reduce their number on a wide variety of food surfaces. Campus Service Activities Student mentor; Member of curriculum, admissions, and awards committees Professional Honors Recipient of one of the Inventors of the Year awards (1995) Recent Publications Zhou, X, Handie, A., Salari, H, Fifer, E., Breen, P. and Compadre, C. “High Performance Liquid Chromatography Determination of Residue Levels on Chicken Carcasses Treated with Cetylpyridinium Chloride.” J. Chromatography B, 728: 273-277, 1999. Goodwin, T., Zhou, X., Haile, P., Breen, P., Anderson, P., Hiller, F.C., and Compadre, C. “Synthesis of 13C, 2H3-Salmeterol: An Analytical Internal Standard for Pharmacokinetic Studies.” J. Labelled Cpd. Radiopharm. 43: 65-75, 2000. Cutter, C. N., Dorsa, W. J., Handie, A., Rodriguez-Morales, S., Zhou, X., Breen, P., and Compadre, C.M.. 1999. "Antimicrobial activity of cetylpyridinium chloride washes against pathogenic bacteria on beef surfaces." J. Food Prot. 63(5): 593-600, 2000. Sumpter,J.A., Breen, P.J., Pasley, J.N., Cheng, R., Ross, M.D., and Compadre, C.M., "The Development of Simulations of Human Physiology in Weightless Environments” IN: Virtual Worlds and Simulations 01, Christopher Landauer and Kirstie L. Bellman, Eds., Society for Computer Simulation International, 2001. Joguparthi, V., Breen, P.J., Compadre, C.C., Zhou, X., Gann, L., Hiller, F.C., and Anderson, P. "Effect of Propellant on the Pharmacokinetics and Pharmacodynamics of Inhaled Albuterol in Asthmatic Subjects." J. Aerosol Med. 16(1): 47-53, 2003. Rodriguez-Morales, S., Zhou, X., Salari, H., Castillo, R., Breen, P.J., and Compadre, C.M. "Liquid Chromatography Determination of Residue Levels on Apples Treated with Cetylpyridinium Chloride." J. Chromatography A, in press, 2004. Recent Patents:
E-mail Address: BreenPhilipJ@uams.edu
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