Request for Proposals


Center for Translational Neuroscience

Department of Neurobiology & Developmental Sciences


Jackson T. Stephens Spine & Neuroscience Institute

College of Medicine

University of Arkansas for Medical Sciences



            The Center for Translational Neuroscience (CTN) requests Full Proposals for research in the area of translational neuroscience.  This NCRR-funded COBRE is designed to increase the number of RO1-funded PIs at UAMS.  The requirements are very specific and the applicants should address any questions to the Director before submitting a proposal (  One award for $50,000 will be made this year.


Who can apply  Only current UAMS faculty (tenure track or non-tenure track) who have never been awarded a NIH R01 grant as PI may apply.  Preference will be accorded to projects involving substantiated collaboration between basic and clinician scientists.  The Project PI should devote a reasonable amount of time and effort (T&E) to the project, but no less than 25%.  The application should specify the identity of a Mentor, an established investigator who will not receive direct support for his/her research, but agrees to mentor the Project PI during the funding period of 12/2008-7/2009. 


How to apply  Applications must be submitted electronically using NIH PHS398 forms in “pdf” format.  The PI is responsible for securing institutional clearance (all human and animal permits secured before an award can be made approximately December 1, 2008).  The application should contain a Face Page, an Abstract page with Key Personnel, a Table of Contents, a NIH-style Biosketch (use current NIH requirements and format) for the PI, Co-I(s) and Mentor, a NIH-style modular budget (cannot include faculty salaries) not exceeding $50,000, a Resources and Environment page, and a ten (10) page proposal (including Specific Aims, Background and Significance, Preliminary Findings (if any), and Experimental Design and Methods).  If applicable, include a Human Subjects section addressing all NIH requirements (including enrollment table, women and children sections), and/or a Vertebrate Animal section addressing all NIH requirements, and Literature cited with full references.  The PI will need to secure IRB and/or IACUC approval before any funds are awarded.  Deadline for submission is September 12, 2008.


Supporting documents  Letter from the PI’s Chair agreeing to release the PI for the stated T&E for the duration of the award, letter of agreement from the Mentor, copy of IRB approval for Human Subject research (if available, but due no later than November 1), copy of IACUC approval for Vertebrate Animal research (if available), copy of certificate for Human Research Subject education training (if applicable), copy of certificate for HIPPA training (if applicable).


Citation requirement  The following citation must be included in all publications (abstracts, articles, chapters, etc.) which used resources (faculty or technician T&E, supplies or equipment) purchased by CTN funds. “Supported by Center of Excellence award  RR020146”.  The Citation requirement elapses one year following the end of NCRR funding (September 1, 2010). In addition, any grant awards received as a result of any CTN support will be reported to the Director immediately upon receipt using NIH PHS398 format for grant support.


Review Process           The External Advisory Committee (EAC) of the Center for Translational Neuroscience will review and rank the proposals submitted based on NIH application criteria (see NIH web site) and COBRE program requirements (see NCRR COBRE RFA web site).  The EAC meeting will take place in October, 2008.  One application will be recommended for further consideration.  The PI may be required to amend the project per the recommendations of the EAC, before submitting the project to NCRR for their approval.  At the time the project is forwarded to the NCRR (~November 1, 2008), the PI will need to provide the following: Other Support information as specified by NIH for each PI, Co-I and Mentor, IRB approval, IACUC approval, copy of Human Subject education certificate, and copy of HIPPA training certificate, if applicable.  Funding is expected no earlier than December 1, and all funds must be spent by July 31, 2009.