Larry Suva, PhD
Associate Professor of Orthopaedic Surgery and Physiology
Director of the Center for Orthopaedic Research |
Doctoral Degree
University of Melbourne, Australia, Medicine
Postdoctoral Training
Department of Bone Biology and Osteoporosis Research, Merck Research
Laboratories, West Point, PA, Cell Biology/Bone Biology
Research Interests
Skeletal complications of malignancy
Bone anabolic agents
Mechanical/hormonal influences on bone and cartilage.
Skeletal phenotyping
G-protein coupled receptors (PTH, Calcium)
OsteomyelitisE-mail
Phone
suvalarryj@uams.edu
501-526-6110 |
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Selected Publications:
Bendre MS, Montague, DC, Peery T, Akel, NS, Gaddy D,
Suva LJ. Interleukin-8 stimulation of osteoclastogenesis and bone resorption
is a mechanism for the increased osteolysis of metastatic bone disease.
Bone. 33:28-37, 2003.
Bendre MS, Gaddy D, Nicholas RW, Suva LJ. Breast Cancer Metastasis to Bone:
It is Not All About PTHrP. Clin Orthop. 415:S39-45, 2003.
Bendre MS, Gaddy-Kurten D, Mon-Foote T, Akel NS, Skinner RA, Nicholas RW,
Suva LJ. Expression of interleukin-8 and not parathyroid hormone-related
protein by human breast cancer cells correlates with bone metastasis in
vivo. Cancer Research 62:5571-5579, 2002.
Nuttall ME, Pendrak I, Emery JG, Nadeau DP, Fisher PW, Nicholson TA, Zhu Y,
Suva LJ, Kingsbury WD Gowen M. Antagonism of oestrogen action in human
breast and endometrial cells in vitro: potential novel antitumor agents.
Cancer Chemotherapy and Pharmacology 47:437-443, 2001.
Nuttall ME, Pendrak I, Emery JG, Nadeau DP, Fisher PW, Nicholson TA, Zhu Y,
Suva LJ, Kingsbury WD, Gowen M. Antagonism of oestrogen action in human
breast and endometrial cells in vitro: potential novel antitumor agents.
Cancer Chemotherapy and Pharmacology 47:437-443, 2001.
Nuttall ME, Stroup GB, Fisher PW, Nadeau DP, Gowen M, Suva LJ. Distinct
mechanisms of action of selective estrogen receptor modulators in breast and
osteoblastic cells. American Journal of Physiology, 279:C1550-C1557, 2000.
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