Selected Publications::

Zharov, P., Mercer, K.E., Glitovskaya, E.N., and Smeltzer, M.S. (2006) Photothermal nanotherapeutics and nanodiagnostics for selective killing of bacteria targeted with gold nanoparticles.  Biophysical Journal, 90(2):  619-627

Leggas, M., Adachi, M. Scheffer, G.L., Sun, D., Wielinga, P., Du, G., Mercer, K.E., Shuang, Y., Panetta, J.C., Jonhston, B., Scheper, R.J., Stewart, C., and Schuetz, J.D. (2004) MRP₄ confers resistance to topotecan and acts as a double agent in protecting the brain from chemotherapy.  Molecular Cell Biology, 24(17):  7612-7621.

Krishnamurthy P., Ross, D.D., Nakanishi, T., Bailey-Dell, K., Zhou, S., Mercer, K.E., Sarkadi, B., Sorrentino, B.P., and Schuetz, J.D. (2004) The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme.  Journal of Biological Chemistry, 279(23):  24218-24225.

Mercer, K.E., Ahn, C., Compadre, C.M., and Drake, R.R. (2002) Mutation of herpesvirus thymidine kinase to generate ganciclovir-specific kinases for use in cancer gene therapy.  Protein Engineering, 15(11):  903-911.

Drake, R.R., Pitlyk, K., McMasters, R.A., Mercer, K.E., Young, H., and Moyer, M.P. (2000) Connexin-independent conference of ganciclovir-mediated killing to bystander effect resistant cell lines by a herpes simplex virus thymidine kinase expressing colon cell line.  Molecular Therapy, 2(5):  515-523.

McMasters, R., Wilbert, T.N., Jones, K.E., Pitlyk, K., Saylors, R.L., Moyer, M.P., Chambers, T.C., and Drake, R.R. (2000) Evaluation of two-drug combinations that increase apoptosis and modulate Bak and Bcl-X_L expression in human colon tumor cell lines transduced with HSV thymidine kinase.  Cancer Gene Therapy, 7(4):  563-573.

McMasters, R., Jones, K.E., Saylors, R.L., Hendrix, E.M. Moyer, M.P., and Drake, R.R. (1998) Lack of baystander killing in HSV-TK transduced colon cell lines due to deficient connexin 43 gap junction formation.  Human Gene Therapy, 9(15):  2253-2261.