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D.
Keith Williams, Ph.D., M.P.H.
Associate Professor
College of Public Health
Department of Biostatistics, Room 3214
Tel. 501.526.6721
Email:williamsdavidk@uams.edu
University of Arkansas Related Links
Williams,
Bursac, Hosmer JSM 2004 Toronto

Hosmer Expedition Oct 2004 A
University of Arkansas for Medical Sciences
UAMS College of Public Health
UAMS Biostatistics

Courses
PBHL 5013
– Biostat
I. (FALL)
COPH-Biostat 1 PBHL 5013 Syllabus Tuesdays 5:30-8:30 8/121
Ed 2
Powerpoint Files
from Mendenhall
Relative Frequency example
Poisson
Profile
Bernoulli
Profile
Worksheets
Worksheet
1
WS 1
Key
Worksheet
2

WS 2
Key
PBHL 5023
– Biostat II. (SPRING)
BOOK FOR
BIOST II: Applied Linear Statistical Models 5th Edition ISBN:
007310874X
Biostat II Spring 2008 Syllabus
Class
notes 1 – 10 -07 (AOV One Way, RBD, Factorial Arrangement of Trts)
AOV homework
1 (includes SAS code, output, and worksheet) 1 – 17
– 08
Key for
AOV homework 1 (Posted 1 – 24 – 08)
Bonf simulation (Posted 1 – 24 – 08)
Powerpoint on
Power (Posted 1 – 24 – 08)
Power
notes (Posted 1 – 24 – 08)
Factorial
Arrangement of Treatments pages from Mendenhall 1-17-08
Power
and Sample Size tables from textbook 1-17-08
Power
and Sample Size Worksheet (Posted 1 – 28 – 08)
Power
and Sample Size SAS Proc GLMPOWER examples (1 – 31 – 08)
Repeated
Measures Analysis. One group,
one factor repeated. Rabbit
data. (1 – 31 – 08)
Repeated
Measures Worksheet (2 – 5 – 08) Please print and bring to class for
discussion on
One
last Repeated Measures Case Study for class discussion. Please bring to class. (2 – 6
– 08)
List of
some covariance structures in proc mixed for use in repeated measure
designs. FYI
Quick
discussion of the advantage of repeated measure design versus non repeated
rabbit data
Matrix
Algebra Notes (2 – 14 – 08)
Key to
repeated measures worksheet (2 – 18 – 08)
Class
notes for chapters 1 through 4 (3 – 6 – 08)
Chapter
1
Chapter
2
Chapter
3
Chapter
4
F and
t-distributions critical value calculator link ( Type in desired
tail area, dfn, and dfd
for F
and df for t. For Bonf
familywise CI’s the ‘B
multiplier’ one tail value is the one you wish, that is,
the alpha/2g value. These
values will be useful for WH and Scheffe Familywise CI’s for values not
our textbook tables. You
might practice on some of our examples to see if you get the correct CI
multiplier values.
Homework
for Chapters 1 – 4. (Muscle Mass data and output passed
out 3 – 6 – 08)
Class
notes for Chapters 6 – 7. (Please print off for 3 – 13
– 08 class meeting)
Computer
Lab Exercise. Partial F Tests ( 3 – 20 – 08)
Worksheet
for Chapters 7 – 8 (Partial F and Dummy Variables) 3
– 20 – 08)
Key for
muscle mass homework (4 – 2 – 08) ( There are two versions of
this problem.
Dummy
variable notes (4 – 3 – 08)
Dummy
variable bump hat book problem (4 – 3 – 08)
SAS
dummy variable class lab exercise (4 – 3 – 08)
Key for
polynomial, partial F test, and dummy variables worksheet (4
– 3 – 08)
Model
building and influence stats plus IRLS example (4 – 17
-08)
Example
of model building JP example (4 – 17 -08)
Example
of influence statistics (4 – 17 -08)
Worksheet
for influence statistics and model building (4 – 22 –
08)
Please
complete so we can discuss it in class
Logistic
Regression 1 Notes (4 – 24 – 08)
Logistic
Regression 2 Notes (4 – 24 – 08)
Print out
and bring the worksheet and printout below to work in class
on May 1. We need to go
over the material before you can complete
this worksheet.
Logistic
Regression Worksheet (4 – 28 – 08)
Print
out that goes with Logistic Regression Worksheet (4 – 28 – 08)
Hosmer
Confounding Example LBW – Smoking Data (4 – 30
– 08)
Logistic
Regression Worksheet Key (5 – 7 – 08)
**


PBHL 5033 – Biostat III. (FALL)
Biostat III
Fall 2006 Syllabus
Class
handout Aug 26 One group repeated measure part 1
Class
handout Aug 26 One group repeated measure part 2
Class handout
Aug 26 Five independent groups with repeated trtmts
Homework
SAS code from Aug 26
Homework
SAS output from Aug 26
GLIMMIX
macro ROBUST logistic macro plus example code
The GLIMMIX and
Robust macro as a SAS file
Powerpoint
‘How to’ Nonparametric Longitudinal Analysis
Code
to run mixed and nonparametric longitudinal analysis on billsept9 data.
F1_ld_f1
Principal
Components SAS example from Sharma Chapter 4

Statistical
Resources
American Statistical Association
Interactive Statistical Calculations
Online Stat Courses from
Statistics.Com
SAS
Starter Kit UCLA
R. A. Fisher

Karl Pearson

Books and
Software
ONLINE SAS EDUCATION FROM
UCLA (HIGHLY RECOMMENDED)
Amazon.com
SAS
NCSS-PASS
PLS example
SAS Nonparametric Longitudinal Macros
William Gossett

GS
Betsy in the Wichita Mountains

Research
Interests
Parametric and nonparametric methods for
longitudinal methods and repeated measures, missing data problems, mixed
models, statistical computing, and simulation.
Recent
Publications
Williams D. Keith. A Generalized test of the Magnitude of Parametric
Assumption Departure for Linear Models in Longitudinal Studies. 2004 Proceedings of the American Statistical
Association, Biometrics Section. pp. 3189-3191, 2005.
Gubbins PO, McConnell
SA, Gurley BJ, Fincher TK, Franks AM, Williams
DK, Penzak SR, Saccente
M. Influence of grapefruit juice on the systemic availability of itraconazole oral solution in healthy adult volunteers.
Pharmacotherapy 24:460-7, 2004.
Kaiser JR, Gauss CH, Williams DK. Surfactant administration acutely affects systemic and
cerebral hemodynamics and gas exchange in very
low birth weight infants. J Pediatr
144(6):809-814, 2004.
Williams DK, Austen MA. A
performance comparison of nonparametric versus generalized linear models in
longitudinal studies. 2003 Proceedings of the American Statistical
Association, Biometrics Section. pp. 4543-4547, 2004.
Bill J. Gurley, PhD, Stephanie F. Gardner, PharmD, EdD, Martha A.
Hubbard, MS, D. Keith Williams, PhD, W. Brooks Gentry, MD, Julie
Carrier, PhD, Ikhlas A. Khan, PhD, David J.
Edwards, PharmD, and Amit
Shah. In vivo
assessment of botanical supplementation on human cytochrome
P450 phenotypes: Citrus aurantium, Echinacea purpurea, milk thistle, and saw
Palmetto. Clinical Pharmacology & Therapeutics
2004;76(5):428-40
Wiseman, Eve J., Williams,
D.K., McMillan, D.E. Effectiveness of payment for reduced carbon
monoxide levels and non-contingent payment on smoking behaviors in
cocaine-abusing outpatients wearing nicotine or placebo patches.
Experimental and Clinical Psychopharmacology in press.
Pyne, Jeffrey M., Rost,
Kathryn M., Farahati , Farah, Tripathi, Shanti P. Smith, Jeffrey Williams, D. Keith, Fortney,
John, and Coyne, James C. One size fits some: the impact of patient
treatment attitudes on the cost-e.ectiveness of a
depression primary-care intervention.
Psychological Medicine, 2004,
34, 1–16. f 2004 Cambridge University Press.
Guide for Technical Reports
Cerebral Autoregulation in
Very-Low-Birth-Weight Infants Kaiser PPT
Cerebral Autoregulation in
Very-Low-Birth-Weight Infants KW JSM 05
Mailing
Address:
D.
Keith Williams M.P.H. Ph.D.
UAMS
College of Public
Health
Department
of Biostatistics
4301
W. Markham St.,
Slot 781
Little Rock, AR
72205-7199
Contact Information
4301 West
Markham, #781
Little Rock, AR
72205-7199
Phone: 501.296.1556
Fax: 501.526.6729
http://www.uams.edu/biostat
Biostatistics
Email
Biostatistics
Webmaster
Last updated: 10/17/2007
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