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D. Keith Williams, Ph.D., M.P.H.

Associate Professor

College of Public Health

Department of Biostatistics, Room 3214

Tel. 501.526.6721

Email:williamsdavidk@uams.edu

 

University of Arkansas Related Links

Williams, Bursac, Hosmer JSM 2004 Toronto

Hosmer Expedition Oct 2004 A

University of Arkansas for Medical Sciences

UAMS College of Public Health

UAMS Biostatistics

Courses

PBHL 5013 – Biostat I. (FALL)

COPH-Biostat 1 PBHL 5013 Syllabus Tuesdays 5:30-8:30 8/121 Ed 2 

Powerpoint Files from Mendenhall

Relative Frequency example

Poisson Profile

Bernoulli Profile  

Worksheets

Worksheet 1     

WS 1 Key           

Worksheet 2              

 

WS 2 Key

PBHL 5023 – Biostat II. (SPRING)

BOOK FOR BIOST II: Applied Linear Statistical Models 5th Edition ISBN: 007310874X

Biostat II Spring 2008 Syllabus

Class notes 1 – 10 -07 (AOV One Way, RBD, Factorial Arrangement of Trts)

AOV homework 1 (includes SAS code, output, and worksheet) 1 – 17 – 08

Key for AOV homework 1 (Posted 1 – 24 – 08)

Bonf simulation (Posted 1 – 24 – 08)

Powerpoint on Power (Posted 1 – 24 – 08)

Power notes (Posted 1 – 24 – 08)

Factorial Arrangement of Treatments pages from Mendenhall 1-17-08

Power and Sample Size tables from textbook 1-17-08

Power and Sample Size Worksheet (Posted 1 – 28 – 08)

Power and Sample Size SAS Proc GLMPOWER examples (1 – 31 – 08)

Repeated Measures Analysis.  One group, one factor repeated.  Rabbit data. (1 – 31 – 08)

Repeated Measures Worksheet (2 – 5 – 08)  Please print and bring to class for discussion on

One last Repeated Measures Case Study for class discussion.  Please bring to class. (2 – 6 – 08)

List of some covariance structures in proc mixed for use in repeated measure designs. FYI

Quick discussion of the advantage of repeated measure design versus non repeated rabbit data

Matrix Algebra Notes (2 – 14 – 08)

Key to repeated measures worksheet (2 – 18 – 08)

Class notes for chapters 1 through 4 (3 – 6 – 08)

     Chapter 1

     Chapter 2

     Chapter 3

     Chapter 4

F and t-distributions critical value calculator link ( Type in desired tail area, dfn, and dfd for F

and df for t. For Bonf familywise CI’s the ‘B multiplier’ one tail value is the one you wish, that is,

the alpha/2g value.  These values will be useful for WH and Scheffe Familywise CI’s for values not

our textbook tables.  You might practice on some of our examples to see if you get the correct CI

multiplier values.

Homework for Chapters 1 – 4.  (Muscle Mass data and output passed out 3 – 6 – 08)

Class notes for Chapters 6 – 7.  (Please print off for 3 – 13 – 08 class meeting)

Computer Lab Exercise. Partial F Tests ( 3 – 20 – 08)

Worksheet for Chapters 7 – 8 (Partial F and Dummy Variables) 3 – 20 – 08)

Key for muscle mass homework (4 – 2 – 08)  ( There are two versions of this problem. 

Dummy variable notes (4 – 3 – 08)

Dummy variable bump hat book problem (4 – 3 – 08)

SAS dummy variable class lab exercise (4 – 3 – 08)

Key for polynomial, partial F test, and dummy variables worksheet (4 – 3 – 08)

Model building and influence stats plus IRLS example (4 – 17 -08)

Example of model building JP example (4 – 17 -08)

Example of influence statistics (4 – 17 -08)

Worksheet for influence statistics and model building (4 – 22 – 08)

Please complete so we can discuss it in class

 

Logistic Regression 1 Notes (4 – 24 – 08)

Logistic Regression 2 Notes (4 – 24 – 08)

Print out and bring the worksheet and printout below to work in class

on May 1.  We need to go over the material before you can complete

this worksheet. 

Logistic Regression Worksheet (4 – 28 – 08)

Print out that goes with Logistic Regression Worksheet  (4 – 28 – 08)

Hosmer Confounding Example LBW – Smoking Data (4 – 30 – 08)

Logistic Regression Worksheet Key (5 – 7 – 08)

 

 

**

PBHL 5033 – Biostat III. (FALL)

Biostat III Fall 2006 Syllabus

Class handout Aug 26 One group repeated measure part 1

Class handout Aug 26 One group repeated measure part 2

Class handout Aug 26 Five independent groups with repeated trtmts

Homework SAS code from Aug 26

Homework SAS output from Aug 26

GLIMMIX macro ROBUST logistic macro plus example code

The GLIMMIX and Robust macro as a SAS file

Powerpoint ‘How to’ Nonparametric Longitudinal Analysis

Code to run mixed and nonparametric longitudinal analysis on billsept9 data.

       F1_ld_f1

Principal Components SAS example from Sharma Chapter 4

Statistical Resources

American Statistical Association

Interactive Statistical Calculations

Online Stat Courses from Statistics.Com

SAS Starter Kit UCLA

R. A. Fisher

Karl Pearson

 

Books and Software

ONLINE SAS EDUCATION FROM UCLA (HIGHLY RECOMMENDED)

Amazon.com

SAS

NCSS-PASS

PLS example

SAS Nonparametric Longitudinal Macros

William Gossett

GS

Betsy in the Wichita Mountains

Research Interests

Parametric and nonparametric methods for longitudinal methods and repeated measures, missing data problems, mixed models, statistical computing, and simulation.

Recent Publications

Williams D. Keith.  A Generalized test of the Magnitude of Parametric Assumption Departure for Linear Models in Longitudinal Studies. 2004 Proceedings of the American Statistical Association, Biometrics Section. pp. 3189-3191, 2005.

Gubbins PO, McConnell SA, Gurley BJ, Fincher TK, Franks AM, Williams DK, Penzak SR, Saccente M. Influence of grapefruit juice on the systemic availability of itraconazole oral solution in healthy adult volunteers. Pharmacotherapy 24:460-7, 2004.

Kaiser JR, Gauss CH, Williams DK. Surfactant administration acutely affects systemic and cerebral hemodynamics and gas exchange in very low birth weight infants. J Pediatr 144(6):809-814, 2004.

Williams DK, Austen MA. A performance comparison of nonparametric versus generalized linear models in longitudinal studies. 2003 Proceedings of the American Statistical Association, Biometrics Section. pp. 4543-4547, 2004.

 

Bill J. Gurley, PhD, Stephanie F. Gardner, PharmD, EdD, Martha A. Hubbard, MS, D. Keith Williams, PhD, W. Brooks Gentry, MD, Julie Carrier, PhD, Ikhlas A. Khan, PhD, David J. Edwards, PharmD, and Amit Shah.  In vivo assessment of botanical supplementation on human cytochrome P450 phenotypes: Citrus aurantium, Echinacea purpurea, milk thistle, and saw

Palmetto.  Clinical Pharmacology & Therapeutics 2004;76(5):428-40

Wiseman, Eve J., Williams, D.K., McMillan, D.E. Effectiveness of payment for reduced carbon monoxide levels and non-contingent payment on smoking behaviors in cocaine-abusing outpatients wearing nicotine or placebo patches. Experimental and Clinical Psychopharmacology in press. 

Pyne, Jeffrey M., Rost, Kathryn M., Farahati , Farah, Tripathi, Shanti P. Smith, Jeffrey Williams, D. Keith, Fortney, John, and Coyne, James C. One size fits some: the impact of patient treatment attitudes on the cost-e.ectiveness of a depression primary-care intervention.

Psychological Medicine, 2004, 34, 1–16. f 2004 Cambridge University Press.

 

Guide for Technical Reports

Cerebral Autoregulation in Very-Low-Birth-Weight Infants Kaiser PPT

Cerebral Autoregulation in Very-Low-Birth-Weight Infants KW JSM 05

Mailing Address:

 

D. Keith Williams M.P.H. Ph.D.

UAMS

College of Public Health

Department of Biostatistics

4301 W. Markham St., Slot 781

Little Rock, AR 72205-7199

 


 

Contact Information

 

4301 West Markham, #781

Little Rock, AR 72205-7199

Phone: 501.296.1556

Fax: 501.526.6729

http://www.uams.edu/biostat

Biostatistics Email

Biostatistics Webmaster

Last updated: 10/17/2007

 

lto:jdthostenson@uams.edu" Biostatistics Webmaster

Last updated: 10/17/2007