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Eric R. Siegel, MS

Research Associate


Fay W. Boozman College of Public Health

Room 3217

Tel.: 501-526-6717




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University of Arkansas

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Statistical Resources

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Interactive Statistical Calculations


Books and Software




Peer-Reviewed Publications

Kaushal V, Kohli M, Dennis RA, Siegel ER, Chiles WW, Mukunyadzi P. Thrombin receptor expression is upregulated in prostate cancer. Prostate. 2006 Feb 15;66(3):273-82.


Kepple J, Layeeque R, Klimberg VS, Harms S, Siegel E, Korourian S, Gusmano F, Henry-Tillman RS. Correlation of magnetic resonance imaging and pathologic size of infiltrating lobular carcinoma of the breast.Am J Surg. 2005 Oct;190(4):623-627.

Santin AD, Bellone S, Van Stedum S, Bushen W, Palmieri M, Siegel ER, De Las Casas LE, Roman JJ, Burnett A, Pecorelli S. Amplification of c-erbB2 oncogene. Cancer. 2005 Oct 1;104(7):1391-1397.


M. Khaidakov, N. Chavannes-Turesky, C. A. Cooney, E. E. Dupont-Versteegden, R. H. Kennedy, E. R. Siegel,  G. Khaidakova,  R. J. Shmookler Reis.  Contribution of de novo Point Mutations to the Overall Mutational Burden in Mitochondrial DNA of Adult Rats.  Exp Gerontol. 2005 May;40(5):396-402. Epub 2005 Mar 28. 


Santin AD, Cane S, Bellone S, Palmieri M, Siegel ER, Thomas M, Roman JJ, Burnett A, Cannon MJ, Pecorelli S.  Treatment of chemotherapy-resistant human ovarian cancer xenografts in C.B-17/SCID mice by intraperitoneal administration of Clostridium perfringens enterotoxin.  Cancer Res. 2005 May 15;65(10):4334-4342.


Santin AD, Bellone S, Siegel ER, Palmieri M, Thomas M, Cannon MJ, Kay HH, Roman JJ, Burnett A, Pecorelli S.  Racial differences in the overexpression of epidermal growth factor type II receptor (HER2/neu): a major prognostic indicator in uterine serous papillary cancer.  Am J Obstet Gynecol. 2005 Mar;192(3):813-818.


Santin AD, Zhan F, Bignotti E, Siegel ER, Cane S, Bellone S, Palmieri M, Anfossi S, Thomas M, Burnett A, Kay HH, Roman JJ, O'Brien TJ, Tian E, Cannon MJ, Shaughnessy J Jr, Pecorelli S.  Gene Expression Profiles of Primary HPV16- and HPV18-Infected Early Stage Cervical Cancers and Normal Cervical Epithelium: Identification of Novel Candidate Molecular Markers for Cervical Cancer Diagnosis and Therapy.  Virology. 2005 Jan 20;331(2):269-291.


Kaushal V, Mukunyadzi P, Dennis RA, Siegel ER, Johnson DE, Kohli M.  Stage-specific characterization of the VEGF-axis in prostate cancer: Expression of lymphangiogenic markers is associated with advanced-stage disease.  Clin Cancer Res. 2005 Jan 15; 11(2):584-593.


Bhattacharyya S, Siegel ER, Petersen GM, Chari ST, Suva LJ, Haun RS.  Diagnosis of Pancreatic Cancer Using Serum Proteomic Profiling.  Neoplasia 2004 Sep/Oct; 6(5):674-686.

Layeeque R, Hochberg J, Siegel E, Kunkel K, Kepple J, Henry-Tillman RS, Dunlap M, Seibert J, Klimberg VS..  Botulinum Toxin Infiltration For Pain Control After Mastectomy And Expander Reconstruction.  Ann Surg. 2004 Oct;240(4):608-614.

Hall G, Hull C, Siegel ER, Smoller BR, Johnson SM.  Seasonal effect upon excision of acquired melanocytic proliferations.  Int J Dermatol. 2003 Sep; 42(9):686-690.

Morris CL, Siegel E, Barlogie B, Cottler-Fox M, Lin P, Fassas A, Zangari M, Anaissie E, Tricot G. Mobilization of CD34+ cells in elderly patients (>/= 70 years) with multiple myeloma: influence of age, prior therapy, platelet count and mobilization regimen. Br J Haematol 2003 Feb; 120(3):413-423.

Cooney CA, Dave AA, Siegel ER, Wolff GL.  Reply to Robert A. Waterland.  J Nutr 2003 Jan; 133(1):239.

Zangari M, Siegel E, Barlogie B, Anaissie E, Saghafifar F, Fassas A, Morris C, Fink L, Tricot G.  Thrombogenic activity of Doxorubicin in myeloma patients receiving Thalidomide: Implications for therapy.  Blood 2002 Aug 15; 100(4):1168-1171.

Zangari M, Saghafifar F, Anaissie EJ, Badros A, Desikan R, Fassas A, Mehta P, Morris C, Toor A, Whitfield D, Siegel E, Barlogie E, Fink L, Tricot G.  Activated protein C resistance in the absence of factor V Leiden mutation is a common finding in multiple myeloma and is associated with an increased risk of thrombotic complications.  Blood Coagulation and Fibrinolysis 2002 Apr; 13(3):187-192.


Badros AZ, Siegel E, Bodenner D, Zangari M, Zeldis J, Barlogie B, Tricot G.  Hypothyroidism in patients with multiple myeloma following treatment with thalidomide.  Am J Med 2002 Apr 1; 112(5):412-413.

Badros A, Barlogie B, Siegel E, Cottler-Fox M, Zangari M, Fassas A, Morris C, Anaissie E, Van Rhee F, Tricot G.  Improved outcome of allogeneic transplantation in high-risk multiple myeloma patients after nonmyeloablative conditioning.  J Clin Oncol 2002 Mar 1 ;20(5):1295-1303.

Badros A, Barlogie B, Siegel E, Roberts J, Langmaid C, Zangari M, Desikan R, Shaver MJ, Fassas A, McConnell S, Muwalla F, Barri Y, Anaissie E, Munshi N, Tricot G.  Results of autologous stem cell transplant in multiple myeloma patients with renal failure.  Br J Haematol 2001 Sep; 114(4):822-829.

Badros A, Barlogie B, Siegel E, Morris C, Desikan R, Zangari M, Fassas A, Anaissie E, Munshi N, Tricot G. Autologous stem cell transplantation in elderly multiple myeloma patients over the age of 70 years.  Br J Haematol 2001 Sep; 114(3):600-607.

Zangari M, Anaissie E, Barlogie B, Badros A, Desikan R, Gopal AV, Morris C, Toor A, Siegel E, Fink L, Tricot G.  Increased risk of deep-vein thrombosis in patients with multiple myeloma receiving thalidomide and chemotherapy.  Blood. 2001 Sep 1; 98(5):1614-1615.

Geigert J, Neidleman SL, Liu TNE, DeWitt SK, Panschar BM, Dalietos DJ, and Siegel ER Production of epoxides from alpha, beta halohydrins by Flavobacterium sp.  Applied and Environmental Microbiology 1983; 45(3):1148-1149. 


Proceedings, Chapters, etc.

Siegel ER. Searching Model Space for SELDI-TOF Cancer Classifiers.  Working Paper, to appear in 2005 Proceedings of the American Statistical Association [CD-ROM], Alexandria, VA: American Statistical Association.

Siegel ER, Thaden J, Simpson PM.  Intra-Slide Correlation and Treatment Significance in Microarray Data:  The Impact of Loess Normalization.  2004 Proceedings of the American Statistical Association [CD-ROM], Alexandria, VA: American Statistical Association, pp. 461-465, 2005.  


Simpson PM, Hamer R, Jo C-H, B. Huang E, Goel R, Siegel E, Dennis R, Bogle ML.  Assessing Model Fit and Finding a Fit Model.  Paper 214-29, SUGI 29 Proceedings, Toronto, May 9-12, 2004. 


Siegel ER, Spencer T, Parrish RS.  Controlling false discovery when planning microarray experiments.  2003 Proceedings of the American Statistical Association [CD-ROM], Alexandria, VA: American Statistical Association, pp3897-3899, 2004.



Mailing Address:


Eric R. Siegel


College of Public Health

Department of Biostatistics

4301 W. Markham St., Slot 781

Little Rock, AR 72205-7199



Contact Information


4301 West Markham, #781

Little Rock, AR 72205-7199

Phone: 501.296.1556

Fax: 501.526.6729

Biostatistics Email

Biostatistics Webmaster

Last updated: 03/01/2007