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Research

Summary of Research Activities

Funded Research

Faculty

Title of Grant

Agency and Acct #

Funding
Period

Gentry WB, Owens SM (PI)

Antibody-Based Therapy for METH Abuse

NIDA R01 DA11560

1/1/98-3/31/09

Gentry WB, Owens SM (PI)

Immunotherapy for Drug Abuse

NIDA R01 DA07610

8/1/99- 6/30/10

Gentry WB (PI on Comp 3), Owens SM (Proj PI)

Antibodies as Biological Interventions for Drug Abuse; Component 3 of Program Project entitled “Preclinical Testing of Antibody Therapy for METH Abuse”

NIDA; P01 DA 14361

9/1/01-7/31/08

Gentry WB (UAMS PI), Holtz RB

Development of Plant Derived Antibodies for Drug Abuse

NIDA R42 DA017596

9/10/04– 6/30/09

Gentry WB, Oliveto A (PI)

Opioid Antagonist Discrimination: A Model of Withdrawl

NIDA R01 DA10017

4/1/06- 3/31/11

Gentry WB, Owens SM (PI)

Active Immunization for Treating Methamphetamine Abuse

NIDA U01 DA023900

9/30/07- 8/31/12

Dobretsov M (PI)

Mechanisms of hyperglycemia induced mechanical hyperalgesia

NIDDK 1 R01 DK067284-01

02/04–01/07

Napolitano CA (PI)

Incidence of Perioperative Ventricular Tachydysrhythmias In Cardiopulmonary Bypass Patients

Ischemic Research & Education Fnd

 

Zabala LM (PI)Schmitz ML, Jaquiss RDB, Imamura M, Martin TW, Bhutta A, Hussain S

A Phase II Multicenter, Randomized, Double-Blind, Parallel Group, Dose-Ranging, Effect-Controlled Study to Determine the Pharmacokinetics and Pharmacodynamics of Sodium Nitroprusside in Pediatric Subjects

NICHD-2003-09-DR

11/06 - present

Unfunded Research Collaborations

Name of Project/Grant

Faculty Involved

Institutions

Length of Project

General Protocol for Draeger Interviews, Surveys and Focus Groups

Block, FE

UAMS

2 yrs

Consumer Preference Testing of the Draeger Medical Systems Infinity Kappa XLT Patient Monitor

Block, FE

UAMS, Drager Medical

1 yr and running

 Interdisciplinary Research 

Name of Project/Grant

Faculty Involved

Institutions

Length of Project

Serum Natriuretic Peptide Assays in Children with Dilated Cardiomyopathy: Correlation of serum levels to echocardiographic functional parameters and Clinical symptoms.

Dyamenahalli U, Morrow WR, Frazier EA, Apuya J, and Kajevska IH

ACH

 

Expression and function of Na+,K+-ATPase in rat calx synapse

Dobretsov M, Von Gersdorff, H

UAMS, Oregon Health Sci U

 

Expression of beta 3 subunit of Na+,K+-ATPase and pain in mice

Dobretsov M, Mogil J, Clark D

UAMS, Pain Genetics Lab, Canada, Stanford

 

Ketamine Pharmacokinetics in Children Undergoing Cardiac Surger

Bhutta A (PI); Stowe C, Schmitz ML, Zabala L, Ullah S, Jaquiss RDB, Imamura M, James L, Watkins WB

ACH

02/07 - present

Pediatric Mobile Cardiac ECMO: A Single Institution Experience

Cabrera A (PI)  Schmitz ML, Fiser R, Imamura M, Jaquiss RDB, Fiser WP

ACH

04/06 - present

Thromboelastogam Blood Analysis of Pediatric Cardiac Surgery Patients

Schmitz ML (PI) Fiser WP, Zabala LM

ACH

04/07 - present

Internet Use by Parents Regarding Their Child¹s Surgical Procedure at Arkansas Children¹s Hospital

 

Schmitz ML (PI) Pierce CD; Martin TW, Killebrew PM, Simpson PM, Zabala LM

ACH

02/07 - present

Obesity Incidence in Children with Congenital Heart Disease

Ray T (PI) Jaquiss RDB, Imamura M, Schmitz ML, Best T.

ACH

02/06 - present

Diagnosis of Hemangiomas and Vascular Malformations Using Non-Invasive Imaging Devices

Stack B (PI), Kokoska M, Shafirstein G, Suen J, Buckmiller L, James CJ, Nicholas R, Schmitz ML, Vural EA.

ACH/UAMS

01/06 - present

 

Entropy and Fractal Pattern of Near Infrared Spectoscopy Measurements in Children with Heart Disease

Bhutta A (PI),Tuzcu V, Nas S, Prodham P, Ullah S, Watkins WB, Zabala LM, Schmitz ML, Imamura M, Jaquiss RDB, Dyamenahalli U

ACH

06/06 - present

Lactate Levels in Children with Atrial Septal Defects Undergoing Surgical Repair

Prodham P (PI); Jaquiss RDB, Bhutta A, Dyamenahalli U, Schmitz ML

ACH

05/06 - present

 

Ultrasonography of Neonatal Blood Vessels: Implications for Vascular Access

Prodhan P (PI); Dyamenahalli U, Schmitz ML, Zabala L, Lyle R, Ullah S

ACH

02/06- present

Use of Ketamine Prior to Cardiopulmonary Bypass in Children

Bhutta A (PI), Fontenot E, Drummond-Webb JJ, Schmitz ML, Anand KS, Kajevska I, James LG, Simpson PM, Ward-Begnoche W

ACH

04/04 - present

A Three Year Retrospective Review of the Use of Aprotinin to Reduce Blood Loss During Idiopathic Scoliosis Surgery at Arkansas Children’s Hospital

Al-Takrouri H (PI), Martin TW, Siddiqui S, Schmitz ML, McCarthy R, Simpson P

ACH

06/06 - present

A Multicenter, Inpatient, Open-Label, within Subject Dose Titration Study to Characterize the Pharmacokinetics/Pharmacodynamics, Safety and Efficacy of Hydromorphone HCl Oral Solution in Subjects from 28 Days to 16 Years of Age, Inclusive, Who Require Opioid Analgesics for Postoperative Pain

Schmitz ML (PI),Sangari TS, Bhutta A, Zabala LM, Guatam NK, Siddiqui MS, Killebrew PM, Pierce CD

ACH and Purdue Pharma L.P

04/07 - present

 

 


Department of Anesthesiology
University of Arkansas for Medical Sciences

4301 West Markham Street, #515
Little Rock, AR 72205
501-686-6114