Design, Biostatistics, and Ethics

Core Services

Design and Biostatistics

Collaborative efforts in Biostatistics generally fall into one of three areas: protocol/grant development, data analysis, and manuscript preparation.
Protocol/Grant Development: Developing grants and protocols is a time consuming effort. Specific areas where statisticians are useful include ensuring that study objectives are clearly stated, proposing appropriate randomization procedures, clearly defining primary and secondary endpoints, proposing appropriate statistical analyses that address each research objective, and providing sample size estimates that ensure the study will have a high probability of meeting its objectives.

Data Analysis: UAMS Biostatistics possesses the resources to complete even the most complex of analyses. The expertise of our faculty and staff represent many areas of the statistical sciences, including survey statistics, psychometrics, clinical trials, signal detection, and bioinformatics. This expertise is essential in determining the appropriate methods to use and in applying them properly. Just as important as the analyses is the ability to communicate the results in an understandable way. In addition to providing written reports, our statisticians discuss these results during one-on-one meetings with the investigators.

Manuscript Preparation: Our statisticians will assist in writing the manuscript when the study is ready for publication. In addition to providing succinct descriptions of the statistical methods, we can provide publication quality tables and graphics that help summarize the data.

Clinical Research Ethics

The TRI Clinical Research Ethics program is administered through the Division of Medical Humanities. The division has achieved a national reputation for its integration of science and human values within the medical education curriculum. In its seminars students move beyond scientific analysis to consider the broader context of healthcare delivery. Our ethicists collaborate with researchers in the initial stages of research design to identify and address ethical or regulatory issues that might arise in the review or implementation of their studies. In addition, ethicists consult with researchers, subject-participants, or regulatory affairs personnel about any ethical concerns that develop during the implementation stages of the study.

UAMS Translational Research Institute
4301 W. Markham #Slot 577, Little Rock, AR 72205, 501-614-2287


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