Herschel Conaway, Ph.D.
Associate Professor
Ph.D., University of Missouri

Office:(501) 686-5125
Fax: (501) 686-8167
Email: ConawayHowardH@uams.edu

Dr. Conaway's research is directed at defining physiological agents which stimulate osteoclasts and bone resorption. Recent studies have included a strong collaborative effort with Professor Ulf H. Lerner, Head, Department of Oral Cell Biology, University of Umea, Sweden.
Dr. Conaway is heavily involved in the teaching of Medical Physiology to medical students and in 1991 received the "Golden Apple Award" from the freshman medical class designating him as the outstanding instructor in the freshmen year. Dr. Conaway also directs and teaches in senior medical student electives and has been presented with "Red Sash" awards on numerous occasions from graduating senior classes for his service. In addition, he is the course coordinator and lectures in the graduate school course, Cellular Endocrinology, as well as lectures in the graduate school course: General Physiology
Dr. Conaway has been the Director of Graduate Studies in the Department of Physiology and Biophysics. He also has served on the campus-wide Graduate School Committee and on the Graduate Student Research Funds Allocation Committee. In addition, Dr. Conaway has served on medical school promotions committees, as a member of the Research Council, in the Physician Educator Honors Program, as Chairman of the Animal Care and Use Committee at UAMS and as the Department of Physiology and Biophysics representative on the Medical School Curriculum Committee.

Representative Publications

Conaway HH, Persson E, Hahlen M, Granholm S, Svensson O, Pettersson U, Lie A, Lerner UH. Retinoids inhibit differentiation of hematopoetic osteoclast precursors. FASEB J. 23: 3526-3538, 2009.

Swanson C, Lorentzon M, Conaway HH, Lerner UH. Glucocorticoid regulation of osteoclast differentiation and expression of receptor activator of nuclear factor-kB (NF-kB) ligand, osteoprotegerin, and receptor activator of NF-kB in mouse calvarial bones. Endocrinology 147:3613-3622, 2006.

Palmquist P, Lundberg P, Persson E, Anders J, Lundgren I, Lie A, Conaway HH, Lerner UH.   Inhibition of hormone and cytokine stimulated osteoclastogenesis and bone resorption by interleukin-4 and interleukin-13 is associated with increased OPG and decreased RANKL and RANK in a STAT6 dependent pathway. J Biol Chem 281:2414-2429, 2006

Schwab AM, Granholm S, Persson E, Wilkes B, Lerner UH, Conaway HH. Stimulation of resorption in cultured mouse calvarial bones by thiazolidinediones. Endocrinology 146:4349-4361, 2005. 

Ahlen J., S. Anderson , H. Mukohyama, C. Roth, A. Blackman, H.H. Conaway, U.H.Lerner. Characterization of the bone resorptive effect of interleukin-11 in cultured mouse calvarial bones. Bone 31: 242-251, 2002

Palmquist P, E. Persson, H.H. Conaway, U.H. Lerner. IL-6, leukemia inhibitory factor, and oncostatin m stimulate bone resorption and regulate the expression of receptor activator of NF-kB ligand, osteoprotegerin, and receptor activator of NF-kB in mouse calvariae. J. Immunol. 169: 3353-3362, 2002

Link to Dr. Conaway at PubMed

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